MOL #97402 1 Activating and inhibitory functions of WNT/ -catenin in the induction of cytochromes P450 by nuclear receptors in HepaRG cells Maria Thomas, Christine Bayha, Silvia Vetter, Ute Hofmann, Michael Schwarz, Ulrich M. Zanger, Albert Braeuning Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, and University of Tuebingen, Tuebingen, Germany (MT, CB, UH, UMZ) Institute of Experimental and Clinical Pharmacology and Toxicology, Dept. of Toxicology, University of Tübingen, Germany (SV, MS) Federal Institute for Risk Assessment, Dept. Food Safety, Berlin, Germany (AB) This article has not been copyedited and formatted. The final version may differ from this version. Molecular Pharmacology Fast Forward. Published on March 30, 2015 as DOI: 10.1124/mol.114.097402 at ASPET Journals on April 8, 2015 molpharm.aspetjournals.org Downloaded from