International Technology and Innovation Research Journal, Volume 1, Issue 1, April 2015 Edition 1 www.itirj.org Review In Chemistry of Amines Authored by: Dr. Nagham Mahmood Aljamali Department, Assist. Professor, Chemistry Department., College of Education. IRAQ Abstract- In this review paper, information about amine compounds, methods of synthesis, reactions, properties, stability, using as catalysis in various reactions in most of organic reactions, test, reactions which containing amine compounds, properties, applications. Keywords- amine, hinsberg reagent ,alkylation, benzenesulfonyl chloride. ——————————  —————————— I. INTRODUCTION omenclature and Structure of Amines In the IUPAC system of nomenclature, functional groups are normally designated in one of two ways. The presence of the function may be indicated by a characteristic suffix and a location number. This is common for the carbon-carbon double and triple bonds which have the respective suffixes (ene) and (yne). Halogens, on the other hand, do not have a suffix and are named as substituents, for example: (CH 3 ) 2 C=CHCHClCH 3 is 4-chloro-2-methyl-2-pentene. If you are uncertain about the IUPAC rules for nomenclature you should review them now. Amines are derivatives of ammonia in which one or more of the hydrogens has been replaced by an alkyl or aryl group. The nomenclature of amines is complicated by the fact that several different nomenclature systems exist, and there is no clear preference for one over the others. Furthermore, the terms primary (1º), secondary (2º) & tertiary (3º) are used to classify amines in a completely different manner than they were used for alcohols or alkyl halides. When applied to amines these terms refer to the number of alkyl (or aryl) substituents bonded to the nitrogen atom, whereas in other cases they refer to the nature of an alkyl group. The four compounds shown in the top row of the following diagram are all C 4 H 11 N isomers. The first two are classified as 1º-amines, since only one alkyl group is bonded to the nitrogen; however, the alkyl group is primary in the first example and tertiary in the second. The third and fourth compounds in the row are 2º and 3º-amines respectively. A nitrogen bonded to four alkyl groups will necessarily be positively charged, and is called a 4º-ammonium cation. For example, (CH 3 ) 4 N (+) Br (–) is tetramethylammonium bromide. The IUPAC names are listed first and colored blue. This system names amine functions as substituents on the largest alkyl group. The simple -NH 2 substituent found in 1º-amines is called an amino group. For 2º and 3º-amines a compound prefix (e.g. dimethylamino in the fourth example) includes the names of all but the root alkyl group. The Chemical Abstract Service has adopted a nomenclature system in which the suffix -amine is attached to the root alkyl name. For 1º-amines such as butanamine (first example) this is analogous to IUPAC alcohol nomenclature (-ol suffix). The additional nitrogen N