Journal of Materials Science and Chemical Engineering, 2015, 3, 87-89 Published Online July 2015 in SciRes. http://www.scirp.org/journal/msce http://dx.doi.org/10.4236/msce.2015.37010 How to cite this paper: Zhao, M. and Shen, G.J. (2015) The Application of Molecularly Imprinted Polymers. Journal of Materials Science and Chemical Engineering, 3, 87-89. http://dx.doi.org/10.4236/msce.2015.37010 The Application of Molecularly Imprinted Polymers Ming Zhao, Guijun Shen College of Environmental and Chemical Engineering, Dalian University, Dalian, China Email: sgj0501@163.com Received April 2015 Abstract Molecularly imprinted technology (MIT) has the characteristics of specificity and high selectivity, which is one of the most promising methodologies. Besides, the polymers are made using MIT as the functional material of solid-phase extraction and chromatographic fractionating and sensor, because of the characteristics of the high selectivity, the better stability and easy preparation. This review introduces the progress in the application of MIT and summarizes its application in the chemistry. Keywords Molecularly Imprinted Polymers, Solid Phase Extraction, Chromatographic Fractionating 1. Introduction Molecular imprinting received a wide range of concerns since the publicly synthesis of molecularly imprinted polymers by Wulff in 1972 [1]. Molecular imprinting technology originated in antigen as template to synthesize antibodies that the template molecule, specific functional monomers and cross-linking agents are to obtain solid polymers. Molecularly imprinted polymers (MIPs), as man-made material of antibodies, possess recognition sites within the polymers that are adapted to the three-dimensional shape [2]. 2. Preparation of MIPs Combin template and functional monomer in the specific dispersion system, adding cross-linking agent (or add- ing sorbent) and initiator, and then that will get the high alternate and robust polymer by non-covalent interac- tion or reversible covalent interaction [3] [4]. Consequentially, the template molecule was washed out from the polymer under harsh physics or chemistry conditions, which obtain a three-dimensional hole can identify the template molecule [5]. MIPs are gaining in importance as robust molecular recognition elements in analytical and separation sciences. What we can do is just to overcome the difficulty of choosing the appropriate condi- tions by chemical synthesis. According to the property of the additive polymer made by template and functional monomers, there are co- valent imprinting and non-covalent imprinting. Covalent imprinting, in which the process is explicit, distinct,