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Int. J. LifeSc. Bt & Pharm. Res. 2013 Obeagu Emmanuel Ifeanyi et al., 2014
HAEMATOLOGICAL EFFECTS OF
FLUTED PUMPKIN (TELFAIRIA OCCIDENTALIS)
LEAVES IN RATS
Obeagu Emmanuel Ifeanyi
1
*, Chikelu Ifeoma M
2
, obarezi Thompson Ndubuisi
3
,
Ogbuabor Bernice Nwakaego
4
and Anaebo Queen Braxton
5
Research Paper
The effects of different concentrations of ethanol extract of fluted pumpkin (Telfairia occidentalis)
leaves on some haematological parameters: Packed Cell Volume (PCV), Haemoglobin (Hb)
concentrations, Total White Blood Cell (TWBC) count and Platelet count were evaluated using
16 Wister strain albino rats as subjects. In the experiment, the rats were divided into 4 groups of
4 rats each and the rats were served different concentrations of T. occidentalis ethanol extract
for seven (7) days. The result showed that the group of rats which received 300 mg/kg and 200
mg/kg leaves extract had a significant increase (p<0.05) in PCV and Hb concentration, those
administered 100 mg/kg of the extract had significant increase (p<0.05) in PCV only. There was
no significant increase (p<0.05) in the WBC and platelet counts of all the groups when compared
with the control. It therefore follows that T. occidentalis has haematopoietic properties.
Keywords: Telfairia occidentalis, Packed Cell Volume (PCV), Haemoglobin (Hb) concentrations,
Total White Blood Cell (TWBC) count and Platelet count
*Corresponding Author: Obeagu Emmanuel Ifeanyi Emmanuelobeagu@Yahoo.com
ISSN 2250-3137 www.ijlbpr.com
Vol. 3, No. 1, January 2014
© 2014 IJLBPR. All Rights Reserved
Int. J. LifeSc. Bt & Pharm. Res. 2014
1
Diagnostic Laboratory Unit, Department of University Health Services, Michael Okpara University of Agriculture, Umudike, Abia State,
Nigeria.
2
Department of Medical Laboratory Science, Faculty of Health Sciences, Madonna University, Elele Campus, Elele, Rivers State, Nigeria.
3
Medical Doctor, Department of University Health Services, Michael Okpara University of Agriculture, Umudike, Abia State, Nigeria.
4
Department of Medical Laboratory Science, Esut Teaching Hopital Parklane,Enugu State, Nigeria.
5
Medical Doctor Department of accident And Emergency Lagos State University Teaching Hospital, Nigeria.
INTRODUCTION
Botanical Description of Fluted Pumpkin
(Telfairia occidentalis) Leaves
Telfairia occidentalis is a tropical vine grown in
West Africa as a leaf vegetable and for its edible
seeds (Badifu et al; 2001). Common name for
the plant include fluted gourd, fluted pumpkin and
ugu in Igbo, gbaroko in Yoruba and umeke in Edo.
This creeping vegetable spread low across the
ground with lobed leaves and long twisting tendrils
(Okoli et al. , 1999). The plant is dioecious,
perennial and drought-tolerant. It thrives best in
soils rich in organic matter and during the early
part of the rainy season. The fruit of the plant is
large and inedible reaching about 13 kg. The seed
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authors
a n d
affiliation