International Journal of Diabetology & Vascular Disease Research, 2013 © 5
Sokolova L.K. Sokolov M.Y (2013) Prevalence of Major Risk Factors for Cardiovascular Disease in Patients With Diabetes. Data from The Ukrainian Endovascular Register.
Int J Diabetol Vasc Dis Res. 1(1), 5-7
International Journal of Diabetology & Vascular Disease Research(IJDVR)
ISSN 2328-353X
Prevalence of Major Risk Factors for Cardiovascular Disease in Patients With Diabetes. Data from The
Ukrainian Endovascular Register
Review Article
Sokolova L.K
1*
. Sokolov M.Y
2
1*
Institute of Endocrinology and Metabolism after V.Komissarenko NAMS of Ukraine, Diabetology Depart-ment, Vushgorodskaya Str, 69, 04114
Kiev, Ukraine
2
Institute of Cardiology after N.Strazhesko NAMS of Ukraine, Department of endovascular surgery and inter-ventional cardiology, 04030 Kiev,
Ukraine
*Corresponding Author:
Sokolova L.K
Institute of Endocrinology and Metabolism after V.Komissarenko
NAMS of Ukraine, Diabetology Department,
Vushgorodskaya Str, 69, 04114 Kiev, Ukraine
E-mail: liubov_sokolova@ukr.net
Receiverd: April 13, 2013
Accepted: April 24, 2013
Published: April 26, 2013
Citation: Sokolova L.K. Sokolov M.Y (2013) Prevalence of Major Risk
Factors for Cardiovascular Disease in Patients With Diabetes. Data from
The Ukrainian Endovascular Register. Int J Diabetol Vasc Dis Res. 1(1),
5-7.
Copyright: Sokolova L.K
©
2013. This is an open-access article distrib-
uted under the terms of the Creative Commons Attribution License,
which permits unrestricted use, distribution and reproduction in any me-
dium, provided the original author and source are credited.
Introduction
Diabetes mellitus (DM), along with cardiovascular and cancer is
one of the irst places among the most seri-ous diseases that aflict
humanity. According to epi-demiological studies of the incidence
of diabetes has doubled every 15 years, by 2025, as predicted by
the International Diabetes Federation (IDF) of their num-ber will
grow to 552 million, with 93-95% of patients included patients
with type 2 diabetes. All over the world, and diabetes was the lead-
ing cause of blindness and kidney failure. In patients with DM in
the 2-3, and according to some studies, up to 6 times higher risk
of stroke and myocardial infarction [1]
The problem of diabetes is also relevant for Ukraine, where there
are more than 1 million 280 thousand peo-ple suffering from dia-
betes, and every year the num-ber increases progressively. Moreo-
ver, on the basis of epidemiological data and the results of com-
paring the prevalence of diabetes in our country to the rate in
neighboring countries, it can be assumed that the true prevalence
of DM in Ukraine in 2-2.5, and probably 3 times more.
In addition, the CD has long been considered not only as an en-
docrine pathology, but as a disease that affects the cardiovascu-
lar system. Namely cardiovascular dis-ease is a major focus for
clinical medicine in diabetes. Found that 75-80% of people with
diabetes die of car-diovascular disease (CVD), with ¾ of these
deaths oc-cur in coronary heart disease (CHD), and others - for
cerebrovascular disease and peripheral vascular disease. CVD is 4
times more common in people with diabetes than in those with-
out diabetes, and 50% of patients at diagnosis of diabetes already
have cardiovascular dis-ease. These indings are relected in the
decision of the national educational experts of the U.S. program
of cholesterol (NCEP ATP III) highlight diabetes as equivalent
to coronary heart disease. Thus, all patients with diabetes are at
high and very high risk of CVD. In addition, there is a tendency
to “rejuvenation” of this disease, so about 50% of the diagnoses
established CVD and 15% of deaths from cardiovascular disease
occur in patients younger than 65 years.
However, the mechanisms that contribute to the high prevalence
and severity of coronary artery disease on the background of
diabetes, are so far poorly under-stood. To date are limited data
on the characteristics of the pathogenesis of atherosclerosis in
patients with diabetes, and found that in terms of diabetes is cru-
cial - potentiation of the classic risk factors of atherosclerosis, or
a fundamental change in its course with mechanisms speciic to
diabetes.
The main purpose of our study was to investigate the incidence
and prevalence of major risk factors for car-diovascular disease in
patients with diabetes and coro-nary artery disease based on the
register interventional procedures department of endovascular
surgery and interventional cardiology NSC “Institute of Cardiol-
ogy after N.Strazhesko “ NAMS of Ukraine
Abstract
The analysis of the incidence of a number of risk factors for coronary heart disease in 2,700 people with angio-graphically documented
coronary atherosclerosis in the electronic register of the Department of Interventional Cardiology in the period from September
1/09/ 2007 to 01/10/2012 was performed. Hypertension, dyslipidemia and multivessel coronary artery lesions were the most frequent
in patients with DM. According to our data the most important risk factor for coronary artery disease in patients with diabetes in
Ukraine is dyslipidemia, the incidence of which is 2.7 times higher than in the group of patients with coronary artery disease without
diabetes.
Keywords: Diabetes Mellitus; Coronary Artery Disease; Hypertension; Dyslipidemia