Emir. J. Food Agric. 2011. 23 (6): 505-510
http://ejfa.info/
505
Antibacterial activity of Minquartia guianensis extracts and
phytochemical evaluation
Lorena M. C. Cursino
1
, Ivanildes Santos
2
, Luis A. M. Mariúba
2
,
Manoel F. Jeffreys
1
, Nerilson M. Lima
1
, Jaciara L. Oliveira
1
,
Patricia P. Orlandi
2
and Cecilia V. Nunez
1*
1
Coordination of Research on Natural Products - CPPN, National Institute of Amazonian
Research - INPA, Av André Araújo, 2936, 69060-001, Manaus, Brazil;
2
Instituto Leônidas e
Maria Deane – ILMD, Fundação Oswaldo Cruz – FIOCRUZ, Manaus, Brazil
Abstract: The species Minquartia guianensis (Olacaceae) is found in the Amazon region and also
in Nicarágua, Panamá and Costa Rica. Indigenous people from Ecuador use the bark infusion for
intestinal infections treatment caused by parasites, against muscular pain and cutaneous irritations.
For this reason, the aim of this work was to evaluate the antibacterial activity of M. guianensis
extracts over Gram-negative (Shigella flexneri M90T, Salmonella choleraesuis 6958, Escherichia
coli E2348/69) and Gram-positive bacteria (Methicillin-Resistant Staphylococcus aureus 33591,
Methicillin-Sensible Staphylococcus aureus 25923, Bacillus cereus 9634, Bacillus liquefaciens
clinical isolated). These bacteria are diarrhea related, which causes several child death in tropical
regions. The active extract is under fractionation (leaf DCM) and until now, four triterpene were
isolated lupeol, taraxerol, lupenona and squalene, but it was not possible yet to assay the
substances, because of their small amount.
Key words: Antibacterial Activity, Minquartia guianensis, Olacaceae, Gram-positive bacteria,
Gram-negative bacteria
Minquartia guianensis
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flexneri M90T, Salmonella choleraesuis 6958, Escherichia coli E2348/69) H &%
- (Methicillin-Resistant Staphylococcus aureus 33591, Methicillin-Sensible Staphylococcus
aureus 25923, Bacillus cereus 9634, Bacillus liquefaciens). I3 > J0(; KL M2@ &% A30
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squalene. Q F<R H S : A34 N6 T GR ’7 8%& F .
*
Corresponding Author, Email: cecilia@inpa.gov.br
Received 11 April 2011; Revised 09 May 2011; Accepted 10 May 2011