© 2010 Wichtig Editore - ISSN 1120-6721 Eur J Ophthalmol ( 0000 ; : 00) 000-000 00 1 INTRODUCTION The emergence of optical coherence tomography (OCT) examinations and the information provided by spectral domain (SD) OCT should not decrease interest in angio- graphy methods, particularly indocyanine green angiogra- phy (ICGA), which is easy to interpret, especially when this imaging modality, valuable for the assessment of subreti- nal pigment epithelium lesions, is not performed with scan- ning laser ophthalmoscopy (SLO). Infrared SLO and ICGA can visualize signs particularly useful for the assessment of choroidal and/or subretinal diseases and characterization of the disease (1-3). In this case of exudative age-related macular degeneration (AMD), polypoidal choroidal va- sculopathy (PCV), and macroaneurysm, only correlations Polypoidal choroidal vasculopathy and macroaneurysm: respective roles of scanning laser ophthalmoscopy–indocyanine green angiography and optical coherence tomography [QUERY: Change in title OK?] Florence Coscas 1,2 , Gabriel Coscas 1,2 , Eric Souïed 1 1 Centre Hospitalier Intercommunal de Créteil, Créteil - France 2 Centre de l’Odeon, Paris - France PURPOSE. To report on a patient with exudative age-related macular degeneration, polypoidal choroidal vasculopathy, and macroaneurysm. METHODS. Scanning laser ophthalmoscopy (SLO)–indocyanine green angiography (ICGA) demonstrated the coexistence of several lesions in the same patient. Optical coherence tomography (OCT) combined with ICGA defined the nature of the lesions and the severity of the exudative phenomena. RESULTS. The eye tracking system ensured precise follow-up of the course of the lesions on both ICGA and spectral domain (SD) OCT. Image correlation provided a precise diagnosis, defining the indications for local and systemic therapy. CONCLUSIONS. In this patient with multiple lesions, only correlation of clinical examinations and SLO-ICG and SD-OCT imaging allowed a complete assessment with the proposal of a coherent and effective treatment plan. KEY WORDS. Age-related macular degeneration, Choroidal polypoidal vasculopathy, Intravitreal injec- tion, Macroaneurysm, Photodynamic therapy, Ranibizumab, SD-OCT, SLO-ICGA, Verteporfin Accepted: July 21, 2010 ORIGINAL ARTICLE among clinical examinations, SLO-ICG, and SD-OCT ima- ging allowed a complete assessment with the proposal of a coherent and effective treatment plan. Case report A 65-year-old man had been treated for wet AMD in the right eye with ranibizumab for 8 months (7 intravitreous in- jections), and obtained only partial improvement. He pre- sented with persistent metamorphopsias. Visual acuity had barely improved since onset of the disorders and remained at 20/80. The patient had a severe allergy to fluorescein with a history of angioneurotic edema. No previous angio- graphic assessment was available. 1.indd 1 2-09-2010 15:10:16