Rethinking low-temperature thermochronology data sampling strategies for quantication of denudation and relief histories: A case study in the French western Alps Pierre G. Valla , Peter A. van der Beek, Jean Braun Institut des Sciences de la Terre, Université Joseph Fourier, CNRS, BP 53, F-38041 Grenoble, France abstract article info Article history: Received 10 December 2010 Received in revised form 29 April 2011 Accepted 2 May 2011 Available online 31 May 2011 Editor: T.M. Harrison Keywords: low-temperature thermochronology numerical modeling inversion exhumation relief development sampling and modeling strategies We assess the importance of thermochronometric data sampling and modeling strategies for correctly estimating mountain belt exhumation. Thermochronological age-elevation proles have been widely used to infer orogenic exhumation histories; however, recent studies have shown that this sampling strategy may not be the most pertinent for quantifying both denudation and relief history. Here, we investigate the ability of combining different thermochronology data sampling schemes with numerical modeling to better constrain denudation rates and relief changes. We produce synthetic thermochronology datasets for real Alpine topography under a specic exhumation and relief scenario using the thermal-kinematic model Pecube. We then adopt an inverse approach based on the Neighborhood Algorithm to quantitatively assess the resolution of different thermochronology datasets collected following elevation proles, long transects and valley bottom sampling. We also test the effect of the modeling approach on denudation and relief predictions, in particular the inuence of the topographic grid resolution and of potential constraints on the geothermal gradient. Our results show that sampling along a single elevation prole does not allow to quantitatively constrain both denudation and relief histories. Numerical outputs clearly evidence tradeoffs that limit the capacity of simultaneously resolving denudation rates and relief change. Quantitative predictions are only slightly different when combining elevation proles along different valleys, but are highly improved when using long transects or valley-bottom samples combined with an elevation prole. The resolution with which relief evolution can be predicted may be increased by a factor of 2 by using spatially distributed datasets. Results of thermal parameter inversions suggest that the geothermal gradient may be better estimated using elevation proles or long-transect sampling rather than using valley bottom samples. Simulations with different model topography resolutions show that degrading the resolution for computational efciency may result in a loss of quantitative information on denudation rates and relief history. In summary, we highlight that both thermochronological sampling strategies and the choice of thermal parameters or model topography resolution have a signicant inuence on predicted denudation and relief histories. Ideally, the sampling strategy should be designed using preliminary modeling of expected denudation and relief histories, and a sensitivity study on assumed thermal parameters and model resolution should be performed when modeling the data. Although our modeling is based on a particular case study of relief evolution in the French western Alps, we believe that these inferences have general relevance for thermochronological studies within mountain belts. © 2011 Elsevier B.V. All rights reserved. 1. Introduction Low-temperature thermochronology has been widely used to quantify the exhumation history of mountain belts (e.g., Braun, 2005; Gallagher et al., 1998; Reiners and Brandon, 2006). Numerous studies in the last 20 yr or so have used apatite ssion-track (AFT) (e.g., Fitzgerald et al., 1995; Gallagher et al., 1998; Hurford, 1991) and (U-Th)/He (AHe) (Ehlers and Farley, 2003; Farley, 2002) data to infer exhumation histories in specic areas. Moreover, low-temperature thermochronology may provide useful constraints for assessing paleo-topography and relief development (e.g., Clark et al., 2005; House et al., 1998; Reiners, 2007). The effect of steady-state topography on thermochronology data is well understood (e.g., Mancktelow and Grasemann, 1997; Stüwe et al., 1994). However, potential effects of time-varying topography, leading to spatially and temporally varying exhumation rates as well as a transient thermal structure, are more difcult to assess (Braun, 2002a; Valla et al., 2010). Thermochronometric sampling strategies have often focused on obtaining age-elevation proles, i.e., datasets of AFT and/or AHe ages collected along a steep elevation transect (e.g., Fitzgerald et al., 1995; Earth and Planetary Science Letters 307 (2011) 309322 Corresponding author. E-mail address: pierre.valla@ujf-grenoble.fr (P.G. Valla). 0012-821X/$ see front matter © 2011 Elsevier B.V. All rights reserved. doi:10.1016/j.epsl.2011.05.003 Contents lists available at ScienceDirect Earth and Planetary Science Letters journal homepage: www.elsevier.com/locate/epsl