THE EFFECTS OF NEUROMUSCULAR TRAINING ON THE GAIT PATTERNS OF ACL-DEFICIENT MEN AND WOMEN Stephanie L. Di Stasi, PT, PhD, OCS 1,3 and Lynn Snyder-Mackler, PT, ScD, SCS, FAPTA 2 Stephanie L. Di Stasi: stephanie.distasi@osumc.edu; Lynn Snyder-Mackler: smack@udel.edu 1 University of Delaware, Biomechanics and Movement Science Program, Newark, DE, USA 2 University of Delaware, Department of Physical Therapy, Newark, DE, USA 3 The Ohio State University, Sports Health and Performance Institute, Columbus, OH, USA Abstract Background—Anterior cruciate ligament rupture is the most common knee ligament injury sustained by active individuals, and the relative injury risk is sex-specific. Women not only demonstrate an increased risk for injury, but also a poorer response following ligament rupture. Perturbation training has shown positive results in healthy females, but gender-specific responses to training after injury have not been evaluated. The purpose of this investigation was to describe the effects of perturbation training on the gait characteristics of male and female non-copers. Methods—Biomechanical data were collected before and after training on 12 male and nine female non-copers using standard motion analysis techniques. Subjects walked at a consistent, self-selected speed over an embedded force plate. Data from both limbs were post-processed and analyzed using a mixed model analysis of variance and minimal clinically important differences to compare the limb behaviors of men and women. Findings—Prior to training, only women demonstrated significant hip joint excursion asymmetry (ES = 1.03; P = 0.009). Minimal clinically important difference values showed the involved limb of the women had reduced hip and knee flexion angles and moments, truncated knee excursions, and increased hip excursions when compared to their own uninvolved limb and the limbs of the male non-copers. Following training, only knee extensor moment values exceeded the minimal clinically important differences in the women. Interpretation—Female non-copers demonstrated unique movement strategies following injury and perturbation training. Women may be a meaningful subgroup of non-copers, and future investigations should consider the effects of gender in the outcomes of non-copers. Keywords anterior cruciate ligament injury; gait; neuromuscular training; gender differences Introduction Neuromuscular training is a type of physical therapy intervention advocated to mitigate movement pattern deficits and abnormalities in a variety of patient populations. In the world © 2011 Elsevier Ltd. All rights reserved. Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. NIH Public Access Author Manuscript Clin Biomech (Bristol, Avon). Author manuscript; available in PMC 2013 May 1. Published in final edited form as: Clin Biomech (Bristol, Avon). 2012 May ; 27(4): 360–365. doi:10.1016/j.clinbiomech.2011.10.008. NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author Manuscript