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Pseudoathetosis: Report of Three
Patients
Mariana Spitz, MD,
*
Alexandre Aluı ´zio Costa Machado, MD,
Rodrigo do Carmo Carvalho, MD,
Fernanda Martins Maia, MD, Monica Santoro Haddad, M
Dagoberto Calegaro, MD, Milberto Scaff, MD, and
Egberto Reis Barbosa, MD
Neurology Department, University of Sa˜o Paulo Medical
School, Sa˜o Paulo, Brazil
Abstract: We reporton 3 patients with pseudoathetosis,
which are involuntary, slow,writhing movements due to
loss of proprioception. © 2006 Movement Disorder Society
Key words: pseudoathetosis; sensoryloss; involuntary
movements
Athetosis is characterized by an inability to retain finger
and toes in a position in which they are placed and by
their continual motion.
1
The term comes from the Greek
word athetosis, meaning “without fixed position” and
was first used by Hammond in 1881.
2
Dooling and Ad-
ams
3
introduced the term pseudoathetosis to refer to a
movementdisorderconsistingofinvoluntary, slow,
writhing movements, clinically indistinguishable from
athetosis, butdue to loss of proprioception, whereas in
true athetosis there is no sensory loss. The lesions re-
sponsible for pseudoathetosis may be located anywhere
along the sensory pathways, from peripheral nerve to
parietalcortex, includingposteriorcolumns and
thalamus.
2,4,5
There are a few reports of pseudoathetosis in literatur
published in English in the last 3 decades.
5
Pseudoath-
etosis has been described in association with multiple
sclerosis, myelitis,
4
leprosy,
6
stroke,
7,8
vitamin B12 de-
ficiency,
9
spinalcord infarct, trauma, tumors, syringo-
myelia,
5
and central pontine myelinolysis.
10
We herein
describe three cases of patients admitted to our service
that were diagnosed with pseudoathetosis.
This article includes Supplementary Video, available online at http:/
www.interscience.wiley.com/jpages/0885-3185/suppmat
*Correspondence to: Dr. Mariana Spitz, Rua Paulo Ce´sar de An-
drade, 200/apto 402, Laranjeiras, Rio de Janeiro 22221-090, Brazil.
E-mail: marianaspitz@hotmail.com
Received 5 October 2005;Revised 1 January 2006; Accepted 24
January 2006
Published online 30 June 2006 in Wiley InterScience (www.
interscience.wiley.com). DOI: 10.1002/mds.21014
1520 M. SPITZ ET AL.
Movement Disorders, Vol.21,No.9, 2006