CLINICAL—ALIMENTARY TRACT
Effect of Institution-Wide Policy of Colonoscopy Withdrawal Time
>7 Minutes on Polyp Detection
MANDEEP S. SAWHNEY,* MARCELO S. CURY,* NAAMA NEEMAN,
‡
LONG H. NGO,
‡
JANET M. LEWIS,*
RAM CHUTTANI,* DOUGLAS K. PLESKOW,* and MARK D. ARONSON
‡
Divisions of *Gastroenterology and
‡
General Internal Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts
See editorial on page 1845.
Background & Aims: Practice guidelines recommend
that endoscopists spend at least 7 minutes examining
the colonic mucosa during colonoscopy withdrawal
to optimize polyp yield. The aim of this study was to
determine if the implementation of an institution-
wide policy of colonoscopy withdrawal time >7 min-
utes was associated with an increase in colon polyp
detection. Methods: All 42 endoscopists at our insti-
tute were asked to attain a colonoscopy withdrawal
time of at least 7 minutes. Compliance with 7-minute
withdrawal time was recorded for all nontherapeutic
colonoscopies. Polyp detection ratio (number of
polyps detected divided by number of colonoscopies
performed) was computed. Regression models were
used to assess the association between compliance
with 7-minute withdrawal time and polyp detection.
Results: During the study period, 23,910 colonosco-
pies were performed. The average age of patients was
56.8 years, and 54% were female. Colon cancer screen-
ing or surveillance was the indication for 42.5% of
colonoscopies. At the beginning of the study, the
polyp detection ratio was 0.48. Compliance with
7-minute withdrawal time for nontherapeutic proce-
dures increased from 65% at the beginning of the
initiative to almost 100%. However, no increase in
polyp detection ratio was noted over the same period
for all polyps (slope, 0.0006; P .45) or for polyps
1–5 mm (slope, 0.001; P .26), 6 –9 mm (slope, 0.002;
P .43), or >10 mm (slope, 0.006; P .13). No
association was detected when only colonoscopies
performed for screening or surveillance were ana-
lyzed. Conclusions: An institution-wide policy of
colonoscopy withdrawal time >7 minutes had no ef-
fect on colon polyp detection.
A
pproximately 145,000 new cases of colorectal cancer
occur every year in the United States, and one third
of these are expected to result in death.
1,2
Several lines of
evidence suggest that colon cancers arise from colon
polyps and that it takes several years for a polyp to
become a cancer.
2–7
This forms the basis for the current
practice of serial colonoscopy at which all visible polyps
are removed. The effectiveness of colonoscopy is depen-
dent, among other factors, on the endoscopist removing
all colon polyps before they become cancerous. Studies of
tandem colonoscopy suggest that up to 27% of colon
polyps may be missed during routine colonoscopy.
8,9
Strategies that improve polyp detection during colonos-
copy are therefore an urgent priority.
Two recent studies have shown that endoscopists who
spend more time examining the colonic mucosa during
colonoscopy withdrawal have a higher likelihood of find-
ing colon polyps than their counterparts.
10,11
While these
studies show an association between mean endoscopist
withdrawal time and the number of polyps found during
colonoscopy, it is not known if requiring all endoscopists
to spend more time examining the colonic mucosa would
improve colon polyp detection. We instituted a quality
improvement initiative at our medical center that re-
quired all endoscopists to spend at least 7 minutes ex-
amining the colonic mucosa while withdrawing the
colonoscope. The aim of our study was to determine if
the implementation of an institution-wide policy of
colonoscopy withdrawal time 7 minutes would be as-
sociated with an increase in colon polyp detection.
Patients and Methods
In February 2006, the Gastroenterology Division
at Beth Israel Deaconess Medical Center in Boston, Mas-
sachusetts, started using colonoscopy withdrawal time as
a marker of colonoscopy quality. Available literature on
colonoscopy withdrawal time was reviewed and discussed
at a staff meeting, and all endoscopists were asked to aim
for a colonoscopy withdrawal time of at least 7 minutes.
Colonoscopy withdrawal times for colonoscopies at
Abbreviations used in this paper: CI, confidence interval.
© 2008 by the AGA Institute
0016-5085/08/$34.00
doi:10.1053/j.gastro.2008.08.024
CLINICAL–
ALIMENTARY TRACT
GASTROENTEROLOGY 2008;135:1892–1898