www.wjpr.net Vol 4, Issue 06, 2015. 456 Hussein et al. World Journal of Pharmaceutical Research INFLUENCE OF THE CRUDE PHENOLIC, ALKALOID AND TERPENOID COMPOUNDS EXTRACTS OF CARDARIA DRABA (LEPIDIUM DRABA L.) ON HUMAN PATHOGENIC BACTERIA Ali Hussein Al-Marzoqi * , Nebras M. Sahi Al-Khafaji and Raad Abaas Kadhim College of Science for Women, Babylon University, PO Box 435, Al-Hillah City, Babylon, Iraq. ABSTRACT Objective: To reveal the effect of the crude phenolic, alkaloid and terpenoid compounds extracts of Cardaria draba (Lepidium draba L.) on some Human Pathogenic Bacteria. Methods: Antibacterial activities of the crude Phenolic, Alkaloid and Terpenoid of medicinal plant were determined by in vitro by agar well diffusion-method against some human pathogenic bacteria. Results: obtained results showed that active compounds of Cardaria draba (Lepidium draba L.) had wide spectrum antibacterial activity against gram-positive and gram-negative bacteria. Conclusion: This study demonstrates that we can conclude that the effect of active compounds in same plant has different effect on different pathogenic organisms in different concentration. KEYWORDS: Antibacterial Activity; Cardaria draba (Lepidium draba L.); Pathogenic Bacteria. INTRODUCTION Nature has been a source of medicinal agents for centuries. The importance of herbs in the management of human ailments cannot be overemphasized. It is clear that the plant kingdom harbors an inexhaustible source of active ingredients valuable in the management of many intractable diseases. [1] Antibiotic resistance has become a global concern. [2] There has been an increasing incidence of multiple resistances in human pathogenic microorganisms in recent years, largely due to World Journal of Pharmaceutical Research SJIF Impact Factor 5.990 Volume 4, Issue 6, 456-460. Research Article ISSN 2277– 7105 *Correspondence for Author Ali Hussein Al-Marzoqi College of Science for Women, Babylon University, PO Box 435, Al-Hillah City, Babylon, Iraq. Article Received on 06 April 2015, Revised on 29 April 2015, Accepted on 22 May 2015