http://mc.manuscriptcentral.com/LongRequest/bit?TAG_ACTI...DE=236767302&SANITY_CHECK_DOCUMENT_ID=1615635&RANDOM=340 Below is a list of the files that were uploaded as well as a summary / cover page. Click on a file name to view the proof of that file. Files are listed in the order specified by the author. Files Uploaded Doc1615635-14479894 Other Cover & Metadata A NON-CONVENTIONAL REACTOR FOR ENZYMATIC SYNTHESIS OF AMPICILLIN Andrea L. O. Ferreira 1 * , Raquel L. C. Giordano 2 , Roberto C. Giordano 2 1 Departamento de Engenharia Química, Universidade Federal do Ceará, Campus do Pici, Bloco 709, CEP 60455-760, Fortaleza – CE, Brazil 2 Departamento de Engenharia Química, Universidade Federal de São Carlos, Brazil. Running title: Non-conventional reactor for ampicillin enzymatic synthesis SUMMARY Nowadays, β-lactam semi-synthetic antibiotics are produced in industry through chemical routes. In spite of its high yield, this process may have high environmental impact. Hence, the enzymatic synthesis of these antibiotics has been receiving increasing attention, since mild reaction conditions may be used. A non- conventional fed-batch reactor is presented here, using a bi-disperse gel matrix for immobilization of the enzyme, http://mc.manuscriptcentral.com/LongRequest/b...2&SANITY_CHECK_DOCUMENT_ID=1615635&RANDOM=340 (1 de 28)31/07/2006 20:23:08