1 Mutant p53 R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high ROS levels. Eyal Kalo # , Ira Kogan-Sakin # , Hilla Solomon, Elad Bar-Nathan, Moshe Shay, Yoav Shetzer, Elya Dekel, Naomi Goldfinger, Yossi Buganim, Perry Stambolsky, Ido Goldstein, Shalom Madar, and Varda Rotter*. Department of Molecular Cell Biology, Weizmann Institute of Science Rehovot, Israel * E-mail: varda.rotter@weizmann.ac.il #These authors contributed equally to this work. © 2012. Published by The Company of Biologists Ltd. Journal of Cell Science Accepted manuscript JCS online publication date 16 August 2012