1 2 Two human host defense ribonucleases against 3 mycobacteria: the eosinophil cationic protein 4 (ECP/RNase 3) and RNase 7. 5 6 7 David Pulido 1 , Marc Torrent 1,2 , David Andreu 3 , M. Victoria Nogués 1 and Ester Boix 1 # 8 9 1 Department of Biochemistry and Molecular Biology, Biosciences Faculty, Universitat 10 Autònoma de Barcelona, Cerdanyola del Vallès, Spain 11 12 2 Present address: Regulatory Genomics and Systems Biology, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom 13 3 Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona Biomedical 14 Research Park, Barcelona, Spain 15 16 17 18 #Corresponding author: 19 Ester Boix 20 Dpt. Biochemistry and Molecular Biology 21 Fac. Biosciences 22 Universitat Autònoma de Barcelona 23 08193 Cerdanyola del Vallès, Spain 24 Tf.: 34-935814147 25 Fax: 34-935811264 26 E.mail: Ester. Boix@uab.cat 27 28 29 30 31 32 33 34 35 RUNNING TITLE: Antimycobacterial RNases 36 37 38 39 40 41 42 43 Copyright © 2013, American Society for Microbiology. All Rights Reserved. Antimicrob. Agents Chemother. doi:10.1128/AAC.00428-13 AAC Accepts, published online ahead of print on 28 May 2013