Impact of moderate and severe hypodontia and amelogenesis imperfecta on quality of life and self-esteem of adult patients Atef Hashem a, *, Alan Kelly b,1 , Brian O’Connell a,2 , Michael O’Sullivan a,3 a Department of Restorative Dentistry & Periodontology, Dublin Dental University Hospital, Lincoln Place, Dublin 2, Ireland b Small Area Health Research Unit (SAHRU), Department of Public Health & Primary Care, Trinity College Centre for Health Sciences, Adelaide & Meath Hospital, Tallaght, Dublin 24, Ireland j o u r n a l o f d e n t i s t r y 4 1 ( 2 0 1 3 ) 6 8 9 – 6 9 4 a r t i c l e i n f o Article history: Received 20 March 2013 Received in revised form 17 May 2013 Accepted 6 June 2013 Keywords: Moderate hypodontia Severe hypodontia Amelogenesis imperfecta Quality of life Self esteem a b s t r a c t Objectives: The objective of this study was to investigate the impact of moderate and severe hypodontia and amelogenesis imperfecta on the quality of life and self-esteem of affected adult patients. Methods: Forty one adult patients (aged 18–45 years) with clinical and radiological diagnoses of moderate to severe hypodontia and twenty seven patients diagnosed with amelogenesis imperfecta were age and gender matched with a control group of patients attending for routine dental care. Subjects completed the Oral Health Impact Profile [OHIP-49] and Rosenberg Self Esteem Scale. A paired t-test was used to analyse data; the test alpha level was set at P  0.05. Results: The results for hypodontia patients were significantly different from controls in six out of the seven OHIP-49 domains, the exception being the Handicap domain. Total scores were also significantly different between the two groups (P = 0.003). Self-esteem was not significantly different between the two groups (P = 0.98). For amelogenesis imperfecta patients the results were significantly different from control patients in four out of the seven domains of the OHIP-49 and also in the total scores (P = 0.01). When self-esteem was investigated there was no significant differences between the two groups (P = 0.92). Conclusions: Moderate to severe hypodontia and amelogenesis imperfecta have marked negative impacts on the Oral Health Related quality of life of this patient population relative to controls. However, self-esteem was not significantly affected. # 2013 Elsevier Ltd. All rights reserved. * Corresponding author. Tel.: +353 1 6127312/242; fax: +353 1 6127297. E-mail addresses: hashema@tcd.ie, atefahashem@yahoo.com (A. Hashem), brian.oconnell@dental.tcd.ie (B. O’Connell), michael.osullivan@dental.tcd.ie (M. O’Sullivan). 1 Tel.: +353 1 8961385/1087. 2 Tel.: +353 1 612 7312; fax: +353 1 612 7297. 3 Tel.: +353 1 6127312/242; fax: +353 1 6127297. Available online at www.sciencedirect.com journal homepage: www.intl.elsevierhealth.com/journals/jden 0300-5712/$ – see front matter # 2013 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.jdent.2013.06.004