Joel Paparello, Irene Zeller, Alison While
Joel Paparello, HIV Specialist Nurse, St Thomas’ Hospital, London; Irene Zeller, Lecturer, Adult Nursing, Florence Nightingale
Faculty of Nursing & Midwifery, King’s College London; Alison While, Emeritus Professor of Community Nursing, Florence
Nightingale Faculty of Nursing & Midwifery, King’s College London
Email: paparello@me.com
Meeting the complex needs of
individuals living with HIV:
a case study approach
ABSTRACT
This article critically discusses the nursing care and management of a
person living with the human immunodeficiency virus (HIV) infection as a
long-term condition, requiring highly complex HIV care. Complex HIV care
is managed in the secondary care setting. However, recent legislation has
motivated shifts in HIV care to the community care setting. This article aims
to enhance health professionals’ understanding in order to equip practice
and district nurses to deliver HIV care provision. Antiretroviral adherence
is a prerequisite for disease survival as well as an essential component of
complete HIV self-care management. It is therefore imperative that nurses
tailor adherence strategies according to each patient’s requirements. Case
management strategies such as the use of cognitive behavioural therapy
to alleviate depressive symptoms will be considered. Furthermore, the use
of motivational interviewing for antiretroviral adherence is highlighted as a
potential intervention to help patients overcome the physical, psychological
and physiological challenges of living with HIV-associated comorbidities.
The delivery of integrated HIV care is pivotal for the management of the
person living with HIV, as is the facilitation of a self-caring behaviour.
KEY WORDS
w HIV w Long-term conditions w HIV-associated depression
w Disease management w Self-management
T
he human immunodeficiency virus (HIV) is
defined as a blood-borne pathogen that has a
direct transmission through blood or body fluids
(Weston, 2008). This blood-borne virus creates exhaustion
within the immune system by the depletion of T-helper
lymphocyte cells known as CD4+ (Bennett and Greenfield,
2013). The reduction of this CD4+ function in the
immune system provokes a suitable microbiological envi-
ronment for the development or restricted prevention of
opportunistic infections; for example, pneumocystis carinii
pneumonia (PCP).
The HIV pathogen instigates the immune hyper-activa-
tion, leading to a rapid increase of viral duplication (Février
et al, 2011). This hyper-activation increases the amount of
HIV viraemia in the person living with HIV, making them
more infectious, increasing the risk of HIV transmission
during sexual intercourse—which then becomes a public
health concern. Another risk of an increase in viraemia
occurs when individuals do not adhere to their HIV
medication, which can affect the ability of the antiretrovi-
ral therapy (ART) to control viral replication, which may
allow ART resistance to develop. Furthermore, depression
is linked with HIV disease progression, decreased physical
immunity, increased plasma viraemia and poor prognosis in
ART adherence regimen (Su et al, 2013).
Importance of ART adherence
ART adherence is a prerequisite for survival for people
with HIV. It is therefore imperative that nurses recognise
and support patients such as Mr Blake (see Box 1) who
are at risk of ART non-adherence. This can be achieved
by redesigning adherence-boosting strategies according to
each patient’s requirements so that a potentially terminal
disease can become a self-care-managed condition.
Resistance to anti-HIV medications is the major factor
that could limit the successful treatment of HIV infection
in Mr Blake’s condition. Resistance results in the anti-HIV
medication no longer being as effective, leading to an
LONG-TERM CONDITIONS
526 British Journal of Community Nursing November 2014 Vol 19, No 11
© 2014 MA Healthcare Ltd
Box 1. Case study discussed in the article
‘Mr Blake’ will be used as a pseudonym in order to protect the person’s pri-
vacy and dignity (Nursing and Midwifery Council, 2008). Mr Blake is a 45-year-
old man of a black ethnic background who has sex with men. He was diag-
nosed with a late HIV infection 10 years ago following a hospital admission
for pneumocystis carinii pneumonia, which is an HIV-associated opportunistic
infection. Mr Blake was unable to cope after his diagnosis and this triggered
further anxiety, and he developed HIV-associated depression. This depression
led to poor antiretroviral therapy (ART) adherence, The patient then developed
ART resistance and HIV progression, which directly affected his HIV progno-
sis. Mr Blake’s inability to deal with these stressors led to further disengage-
ment with his HIV care. This disengagement allowed the HIV to progress,
resulting in an increase of serum HIV viraemia and a reduction of immune
functionality, at which point Mr Blake required a further admission to hospital.
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