Hindawi Publishing Corporation
Case Reports in Transplantation
Volume 2013, Article ID 197524, 3 pages
http://dx.doi.org/10.1155/2013/197524
Case Report
Acute Renal Failure and Volume Overload
Syndrome Secondary to a Femorofemoral Arteriovenous Fistula
Angioplasty in a Kidney Transplant Recipient
Dominique Bertrand, Geoffroy Desbuissons, Nicolas Pallet, Albane Sartorius,
Christophe Legendre, Marie-France Mamzer, and Rebecca Sberro Soussan
Service de Transplantation R´ enale et Soins Intensifs, Hˆ opital Necker, Assistance Publique Hˆ opitaux de Paris,
Universit´ e Paris Descartes, 75015 Paris, France
Correspondence should be addressed to Nicolas Pallet; npallet@yahoo.fr
Received 8 January 2013; Accepted 30 January 2013
Academic Editors: P. A. Andrews, M. G. H. Betjes, and M. Sadeghi
Copyright © 2013 Dominique Bertrand et al. his is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
Experimental and clinical studies analyzing the impact of AVF on cardiovascular and renal parameters, as well as outcomes, in
kidney transplant recipients are lacking. On the other hand, it is not known whether AVF ligation ater transplantation modiies
hemodynamic parameters and kidney function. We report a case of a renal transplant recipient who developed an acute congestive
heart failure accompanied by renal failure, which were triggered by femorofemoral AVF angioplasty. Prompt AVF ligation
rapidly reversed clinical symptoms and normalized cardiac and renal functions. his paper illustrates the potential deleterious
consequences of high-output AVF ater kidney transplantation and raises considerations regarding the impact of the istula on
cardiac status and kidney function ater kidney transplantation and, consequently, the management AVF ater transplantation.
1. Introduction
Arteriovenous istula (AVF) is the preferred access for
hemodialysis, because of its longevity and resistance to
infections [1]. However, large let-to-right shunts generate
hemodynamic disturbances that may be deleterious for the
cardiovascular system [2]. AVF induces a drop in peripheral
vascular resistance, which leads to a compensatory increase
in cardiac output. Sympathetic nervous system is activated,
leading to an increasing pulse rate, stroke volume, and
contractility.
If high-output cardiac failure is underrecognized during
hemodialysis, because of the absence of obvious volume
overload, the deleterious cardiovascular efect of AVF can
occur ater kidney transplantation. However, experimental
and clinical studies analyzing the impact of AVF on cardio-
vascular and renal parameters, as well as outcomes, in kidney
transplant recipients are lacking.
On the other hand, it is not known whether AVF ligation
ater transplantation modiies hemodynamic parameters and
kidney function. here is no consensus regarding AVF man-
agement ater kidney transplantation, and istula are usually
ligated according to the patient wishes and if the clinical
situation is controlled.
Here we report a case of a renal transplant recipient with a
femorofemoral AVF who developed an acute congestive heart
failure accompanied by renal failure, which were triggered by
AVF angioplasty. Prompt AVF ligation rapidly reversed clin-
ical symptoms and normalized cardiac and renal functions.
2. Case
A 51-year-old Caucasian woman was admitted to our depart-
ment in April 2011 for a third kidney transplantation. Focal
segmental glomerulosclerosis (FSGS) has been diagnosed
in 1973, and the patient reached end-stage renal failure in
1982. He received two kidney allograts, in 1983 and 1993,
which both failed as a consequence of early recurrence of
FSGS. Since 2002, hemodialysis was performed on a let