International Journal of
Food and Nutritional Science
Int J Food Nutr Sci | Volume 2: Issue 6 1 DOI: 10.15436/2377-0619.15.e005
Copy rights: © 2015 Kuzmar, I. This is an Open access article distributed under the terms of Creative Commons
Attribution 4.0 International License.
Editorial
Isaac Kuzmar
1,2,3*
, Maira Zalabata
3
Corresponding author: Isaac Kuzmar, MD, MBI-MBT, MsCN, MBA, PhD, International Medical Health Care and Scientiic
Research, BiomediKcal, Europe and America, Tel:+3580449198098; E-mail: isaac.kuzmar@biomedikcal.com
Received Date: December 02, 2015 Accepted Date: December 03, 2015 Published Date: December 05, 2015
Introduction
A genome is an organism’s complete set of DNA, including all of its genes; a copy of the entire genome is contained in
all cells that have a nucleus. All of us carry in our cells the genetic code (DNA) which is a kind of huge library that contains all the
information needed to make a human being and not just any, but a concrete one. Mine used to do to me, you and yours, although we
share the most information, each has its own library. This library is written in the DNA, a long molecule in which the instructions
are inserted in four different chemical molecules: adenine, guanine, cytosine and thymine. Are like the four letters of the alphabet,
in scientiic articles, are represented by the initials A, G, C and T.
Migration, the ability to travel massive, the food industry, which facilitates obtaining food in towns and cities across the
world, leads to an increased energy intake and a decrease in physical activity.
Hippocrates preached the importance of nutrition in health was “rediscovered” in the twentieth century. Scientiic societies,
NGOs, global organizations have been publishing comprehensive recommendations to reduce common diseases that affect public
health. But this effort has been limited, since it does not include the genetic individuality of world populations. This may be the
answer to why a global recommendation has not been successful in some populations
[1]
.
In 1999, the rapid changes in the prevalence of obesity lead the Centers for Disease Control and Prevention’s (CDC’s) to
recognize the obesity epidemic as a US national problem and in a short term a worldwide problem
[2]
. The prevalence of obesity has
increased during the last decades and varies from 10-20% in most European countries to approximately 32% in the United States
[3]
.
Obesity is a multifactorial disorder that has multiple and serious biological health side effects of those affected
[4]
. Conditions that are
developed from multiple causes
[5]
: environmental and behavioral factors, underlying diseases and socioeconomic status, including
genetic predisoposition
[6]
.
Nutrigenomics examines the association of exogenous nutrients and molecular responses to maintain homeostasis in an
individual
[7]
.
Many strategies to promote weight loss are being explored as antiobesity treatments
[8]
, patient dropout can lead to treatment
failure, and it is important to identify predictors of treatment adherence to improve the success of these programs
[9]
. It is necessary to
provide all nutrition consultations with global guidelines and novel tools in order to diagnose and to treat in an effective way obesity.
In recent years, the genetic determinants of obesity and metabolic syndrome were largely unknown, with the exception of
a few forms of monogenic extreme obesity; since genome-wide association studies (GWAS) became available, large advances have
been made
[10]
.
Research on how interactions between candidate genes and environmental factors inluence illnesses has generated en-
thusiasm but not many replicable indings
[11]
. We had the the concept that our environment has changed, but our genome has re-
Food, Genomic and Nutrigenomic:
Fighting the Obesity Epidemic
1
International Medical Health Care and Scientiic Research, BiomediKcal, Europe & America
2
Doctor, Kainuun SOTE, Kajaani, Finland
3
Research, Development and Innovation Department, Kuzmar Biotech, London, United Kingdom & Manizales, Colombia
Citation: Kuzmar,I., et al. Food, Genomic and Nutrigenomic: Fighting the Obesity Epidemic. (2015) Int J Food Nutr Sci 2(6): 1-2.