Pictorial essay
Diuretic contrast-enhanced magnetic resonance urography versus
intravenous urography for depiction of nondilated urinary tracts
T. El-Diasty, O. Mansour, A. Farouk
Department of Radiology, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt
Received: 1 December 2001/Accepted: 5 January 2002
Abstract
Diuretic contrast-enhanced magnetic resonance urogra-
phy (MRU) is analogous to conventional intravenous
urography (IVU) and, hence, designated as excretory
MRU. It is performed with a T1-weighted fast gradient-
echo sequence to obtain breath-hold, dynamic MRU after
intravenous injection of low-dose furosemide (5–10 mg)
and gadolinium (Gd) chelate. The combination of Gd and
furosemide is the key for achieving a uniform distribution
of the contrast material inside the entire urinary tract. It
provides high-resolution images of nondilated urinary
tracts and information about the renal function. This pic-
torial essay reviews the technical aspects and practical
consideration of diuretic Gd-enhanced MRU and un-
derlines its diagnostic capability in comparison with
IVU in the depiction of nondilated collecting systems.
We discuss its potential applications, as in young pa-
tients with anatomic anomalies, patients with renal
transplants, patients allergic to iodinated contrast me-
dium, and avoiding multimodality work-up in the eval-
uation of kidney donors and patients with renal and
extrarenal tumor diseases.
Key words: Magnetic resonance imaging—Urography—
Gadolinium—Furosemide—Nondilated urinary tract.
Intravenous urography (IVU) has been considered the
gold standard for evaluating the urinary tract. However, it
uses ionizing radiation and requires iodinated contrast
medium [1]. On unenhanced T2-weighted magnetic res-
onance (MR) urograms, the nondilated urinary tract is
invisible or incompletely visualized, whereas excellent
depiction can be achieved with T1-weighted, gadolinium
(Gd)– enhanced MR urography (MRU). T1-weighted
MRU imitates conventional X-ray urography and, hence,
is referred to as excretory MRU. With this technique,
sequences are obtained after renal excretion of an intra-
venously injected Gd chelate [2]. The fast spoiled gradi-
ent-echo (GRE) sequence used to evaluate the vessels in
MR angiography also can be used to visualize contrast
medium in the collecting system [3].
In their initial experimental study, Nolte-Ernsting et
al. [4] presented the advantages of this imaging technique
in retrieving high-resolution spatial images in nonob-
structed urinary tracts. Also, in contrast to heavily T2-
weighted fast spin-echo sequences, image quality was not
influenced by superimposed abdominal fluid collections.
Further, the excretory function of the kidneys could be
evaluated. The need for a diuretic to optimize the endolu-
menal concentration of Gd and to produce accelerated
distention was addressed.
The purpose of this article was to demonstrate the
potential usefulness of diuretic Gd-enhanced (DG) MRU
and compare it with IVU for the depiction of nondilated
urinary tracts.
T1-weighted, excretory MRU
Static-fluid MRU uses nonenhanced, heavily T2-
weighted pulse sequences. It is less suitable for imaging
Award-winning poster presented at the 8th European Symposium on
Urogenital Radiology; Rotterdam, The Netherlands; 14 –16 September
2001
Correspondence to: T. El-Diasty
Abdom Imaging 28:135–145 (2003)
DOI: 10.1007/s00261-002-0010-x
Abdominal
Imaging
© Springer-Verlag New York Inc. 2003