Wiehe, A.; Shaker, Y. M.; Brandt, J. C.; Mebs, S.; Senge, M. O. (2005): Lead structures for applications in photodynamic therapy. 1. Synthesis and variation of m-THPC (Temoporfin) related amphiphilic A 2 BC–type porphyrins. Tetrahedron 61, 5535–5564. Graphical Abstract Lead structures for applications in photodynamic therapy: 1. Synthesis and variation of m-THPC (Temoporfin) related amphiphilic A 2 BC-type porphyrins Arno Wiehe, Yasser M. Shaker, Johan C. Brandt, Stefan Mebs and Mathias O. Senge * HN N N NH OH A A B hydrophilic or hydrophobic groups