Research Article Geographic Tongue and Fissured Tongue in 348 Patients with Psoriasis: Correlation with Disease Severity Bruna L. S. Picciani, 1 Thays T. Souza, 1 Vanessa de Carla B. Santos, 1 Tábata A. Domingos, 1 Sueli Carneiro, 2 João Carlos Avelleira, 3 David R. Azulay, 3 Jane M. N. Pinto, 4 and Eliane P. Dias 1 1 Hospital Universit´ ario Antonio Pedro, Faculdade de Medicina, Departamento de Patologia, Universidade Federal Fluminense, Rua Marques de Parana 303, 4 ∘ Andar, 24033-900 Niteroi, Rio de Janeiro, RJ, Brazil 2 Sector of Dermatology, Rio de Janeiro Federal University, Rio de Janeiro, Brazil 3 Department of Dermatology Rubem David Azulay, Santa Casa da Miseric´ ordia, Rio de Janeiro, Brazil 4 Department of Dermatology, Universidade Federal Fluminense, Rio de Janeiro, Brazil Correspondence should be addressed to Bruna L. S. Picciani; brunapicciani@yahoo.com.br Received 31 July 2014; Revised 23 December 2014; Accepted 27 December 2014 Academic Editor: Uwe Wollina Copyright © 2015 Bruna L. S. Picciani et al. his is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Geographic tongue (GT) and issured tongue (FT) are the more frequent oral lesions in patients with psoriasis. he aims of this study were to compare the prevalence of GT/FT between psoriasis group (PG) and healthy controls (HC) and investigate the correlation between GT/FT and psoriasis severity using the PASI and age of psoriasis onset. hree hundred and forty-eight PG and 348 HC were selected. According to the age of psoriasis onset, the individuals were classiied as having early psoriasis and late psoriasis. he severity of vulgaris psoriasis was determined according to PASI. A follow-up was conducted in patients with psoriasis vulgaris (PV) with GT to evaluate the progression of oral and cutaneous lesions. he FT and GT were more frequent in PG than in HC. he incidence of GT was higher in patients with early psoriasis and that of FT in late-psoriasis. here is association between psoriasis intensity and GT; and a higher monthly decrease of PASI score in patients without GT. he presence of GT and FT is higher in PG than in the HC. GT is associated with disease severity and may be a marker of the psoriasis severity. 1. Introduction Psoriasis is a common inlammatory cutaneous disease afecting 1%–3% of the world population [1]. he presence of oral lesions in psoriasis is uncommon and controversial [2–5]. Some reports have stated that oral lesions do not occur in psoriasis [6], and some have reported that they rarely occur [7, 8]. he oral manifestations of psoriasis mostly include nonspeciic lesions such as geographic tongue (GT) and issured tongue (FT). In addition, it has been also considered that these conditions are associated with psoriasis [2–4]. GT presents with clinical, histological, and genetic patterns similar to those of psoriasis, suggesting that this lesion may represent an oral manifestation of psoriasis [3, 4, 9, 10]. However, some authors have questioned this because GT usually appears without cutaneous lesions [8, 11, 12]. Gonzaga and Consolaro showed that GT may be a failed form of psoriasis that proceeds with or without subse- quent simultaneity [13]. A positive family history, an asso- ciation between psoriasis and GT, and the presence of the histocompatibility antigen HLA-Cw6 suggest a genetic basis, providing further evidence that these disorders are related [10]. Moreover, increased GT occurrence in patients with severe psoriasis vulgaris suggests that this lesion may be a marker of psoriasis severity [14–16]. his study aimed to compare the prevalence of GT/FT between PG and healthy controls (HC) and investigate the correlation between GT/FT and psoriasis severity using the Psoria- sis Area and Severity Index (PASI) and age of psoriasis onset. Hindawi Publishing Corporation e Scientific World Journal Volume 2015, Article ID 564326, 7 pages http://dx.doi.org/10.1155/2015/564326