DOI: 10.1126/scitranslmed.3008895 , 241ra78 (2014); 6 Sci Transl Med et al. Shimpei Kasagi Autoimmunity Without Compromising Antibacterial Immune Response Generated Antigen-Specific Regulatory T Cells Treat - In Vivo Editor's Summary autoimmunity. antigen-specific regulatory T cells. If these data hold true in humans, this may be a champion approach for treating , which was critical for the induction of the β - cells induced phagocytes to produce transforming growth factor autoimmune response without affecting the immune response to a bacterial antigen. They found that the apoptotic peptides, which resulted in antigen-specific regulatory T cell differentiation in vivo. These cells suppressed the experimental autoimmune encephalomyelitis or nonobese diabetes. The authors then introduced autoantigenic tolerance in mice with established autoimmune disease. They induced apoptosis of immune cells in mice with either . now use the same approach to restore et al however good, and start over with a fresh group of youngsters. Kasagi trade the more experienced players, -- Sometimes for a sports team to pull out of a slump, they need to rebuild Rebuilding Immunity http://stm.sciencemag.org/content/6/241/241ra78.full.html can be found at: and other services, including high-resolution figures, A complete electronic version of this article http://stm.sciencemag.org/content/suppl/2014/06/17/6.241.241ra78.DC1.html can be found in the online version of this article at: Supplementary Material http://stm.sciencemag.org/content/scitransmed/5/211/211ra157.full.html http://stm.sciencemag.org/content/scitransmed/3/83/83ra41.full.html http://stm.sciencemag.org/content/scitransmed/4/125/125sr1.full.html can be found online at: Related Resources for this article http://www.sciencemag.org/about/permissions.dtl in whole or in part can be found at: article permission to reproduce this of this article or about obtaining reprints Information about obtaining is a registered trademark of AAAS. Science Translational Medicine rights reserved. The title NW, Washington, DC 20005. Copyright 2014 by the American Association for the Advancement of Science; all last week in December, by the American Association for the Advancement of Science, 1200 New York Avenue (print ISSN 1946-6234; online ISSN 1946-6242) is published weekly, except the Science Translational Medicine on June 23, 2014 stm.sciencemag.org Downloaded from on June 23, 2014 stm.sciencemag.org Downloaded from