Title Page Title: The Indispensable Soma Hypothesis: Up-regulation of somatic repair through significant information-sharing Author: M. Kyriazis MD Institution: ELPIs Foundation for Indefinite Lifespans, York Road, London TW10 6DR Correspondence: Marios Kyriazis, York Road, London TW10 6DR, tel: 0044 (0)7850221796, email: drmarios@live.it Grants: Nil declared