165 © 2011 Società Italiana di Nefrologia - ISSN 1121-8428
DOI:10.5301/JN.2010.2380
JN ( 2011; : 02) 165-176 24 EPHROL
ABSTRACT
Background: Few reports have addressed how current
practice reflects uncertainty as to the optimal man-
agement of renal replacement therapy (RRT) in West-
ern countries. Current dialytic practice for 2007 in the
northwest of Italy was assessed.
Methods: A total of 24 nephrology and dialysis centers
covering all of the RRT provided in the intensive care
units (ICUs) in northwest Italy took part in the survey.
Consultant nephrologists of each center reported their
own activities throughout the year 2007 by an e-mailed
questionnaire.
Results: RRT for a total of 7,842 days was provided
by 24 dialysis centers in 79 ICUs for 1,118 patients.
RRT median duration (5.76 days/patient) increased
with the increasing number of hospital ICU beds. Of
the RRT cases, 69.9% were due to acute kidney in-
jury, 23.6% for continuation of a treatment in chronic
dialysis patients and 4.2% for extrarenal indications.
1
Nephrology and Dialysis Unit, CTO Hospital, Turin - Italy
2
Nephrology and Dialysis Unit, Giovanni Bosco Hospital,
Turin - Italy
3
Nephrology and Dialysis Unit, Santa Croce e Carle
Hospital, Cuneo - Italy
4
Nephrology and Dialysis Unit, Mauriziano Hospital, Turin
- Italy
5
Nephrology, Dialysis and Transplantation Unit, Molinettte
Hospital and Nephrology and Dialysis Unit, Civile
Hospital, Chivasso, Turin - Italy
6
Nephrology and Dialysis Unit, S.S. Antonio e Biagio
Hospital, Alessandria - Italy
7
Nephrology, Dialysis and Transplantation Unit, OIRM
Hospital, Turin - Italy
8
Nephrology and Dialysis Unit, Umberto Parini Hospital,
Aosta - Italy
9
Nephrology and Dialysis Unit, Maggiore Hospital, Novara
- Italy
Filippo Mariano
1
, Marco Pozzato
2
, Giorgio Canepari
3
,
Corrado Vitale
4
, Francesca Bermond
5
,
Colombano Sacco
6
, Alessandro Amore
7
,
Massimo Manes
8
, Carlo Navino
9
; Piedmont
and Aosta Valley Section of Italian Society of
Nephrology
Collaborators: Andrea Campo (Alba, CN), Dario
Sassone (Asti), Gianmario Bosticardo (Biella), Paola
Carpani (Borgomanero, NO), Giovanni Calabrese
(Casale Monferrato, AL), Marco Formica (Ceva, CN),
Emanuele Stramignoni (Chieri, TO), Alfonso Pacitti
(Chivasso, TO), Andrea Serra (Cirie’, TO), Franco
Bonello (Ivrea, TO), Antonio Marciello (Pinerolo,
TO), Vincenzo Todini (Rivoli, TO), Carmelina di Tullio
(Torino), Cesare Guarena (Torino), Maurizio Borzumati
(Verbania), Gianenrico Guida (Vercelli)
Renal replacement therapy in intensive care
units: a survey of nephrological practice in
northwest Italy
ORIGINAL ARTICLE
More than 90% of the patients were treated with
high permeability membranes, at a median target
dosage of 35.0 ml/kg per hour in continuous (39.4%)
or extended modality (6-14 hours, 38.5%). Unfrac-
tionated heparin was the most common anticoagu-
lant used (67.5%, median 500 IU/hour). In patients at
high risk of bleeding, RRT without or with heparin at
low-dose + saline flushes was the most commonly
adopted line of treatment, followed by citrate (18%
of days of dialysis). The decision to start RRT was
made by nephrologists alone or in collaboration
with intensivists, whereas dose prescriptions were
given by nephrologists alone.
Conclusions: This survey may represent a useful
starting point for further research into changes in
RRT practice and the adoption of common, shared
protocols.
Key words: Critically ill patients, Northwest Italy, Re-
nal replacement therapy, Survey