Acta Clin Croat, Vol. 46, No. 2, 2007 % M. Vuèiæ et al. Peripancreatic bronchogenic cyst Acta Clin Croat 2007; 46:171-174 Case Report RETROPERITONEAL PERIPANCREATIC BRONCHOGENIC CYST MIMICKING PANCREATIC CYSTIC TUMOR Majda Vuèiæ, Davor Tomas, Mario Zovak 1 , August Mijiæ 1 and Boo Krulin Ljudevit Jurak University Department of Pathology and 1 University Department of Surgery, Sestre milosrdnice University Hospital, Zagreb, Croatia SUMMARY Retroperitoneal cystic tumors are rare and among them retroperitoneal bronchogenic cysts are extremely infrequent. Bronchogenic cyst is a development abnormality of the primitive foregut, which typically occurs in the chest. We describe a rare case of isolated peripancreatic bronchogenic cyst in a 53-year-old-man that presented with intermittent epigastric pain. Abdominal ultrasonography and computed tomography showed a cystic lesion closely related to the superior border of the pancreatic tail. The cystic tumor of pancreas was suspected. The cystic lesion was surgically removed and submitted for histopathologic analysis. Microscopically, the cyst was partially lined with pseudostratified, columnar, ciliated respiratory-type epithelium and partially with a single layer of tall columnar epithelial cells interspersed occasionally with goblet cells, which resided on the fibromuscular wall that contained seromucinous glands, and focally dense inflammatory cells. The diagnosis of bronchogenic cyst was established. Although rare in this region, bronchogenic cyst should be considered on differential diagnosis of peripancreatic cystic lesions. Key words: Bronchogenic cyst complications; Bronchogenic cyst diagnosis; Pancreatic neoplasms pathology; Pancreatic neoplasms diagnosis; Retroperitoneal neoplasms diagnosis; Retroperitoneal neoplasms pathology; Retroperitoneal neoplasms surgery Correspondence to: Majda Vuèiæ, Ljudevit Jurak University Department of Pathology, Sestre milosrdnice University Hospital, Vinogradska c. 29, HR-10000 Zagreb, Croatia E-mail: mvucic@kbsm.hr Received January 19, 2007, accepted in revised form May 21, 2007 Introduction Bronchogenic cysts are congenital foregut abnormal- ities resulting from embryological budding of the bron- chial tree. Generally, they are found in the posterior part of the mediastinum, particularly posterior to the carina and intrapulmonary regions 1,2 . However, they can rarely occur in such unusual sites as the skin, subcutaneous tissue, pericardium, and even more rarely in the retro- peritoneum 3 . Subdiaphragmatic bronchogenic cysts usu- ally are asymptomatic and are mostly an incidental find- ing. In the peripancreatic region, bronchogenic cysts are extremely rare and clinically and radiologically mimic pancreatic psudocysts or cystic tumors 4 . The recom- mended treatment for bronchiogenic cyst is surgical extirpation, to establish the diagnosis, remove the symp- toms and prevent complications 5 . We report a case of a 53-year-old man with retroperitoneal bronchogenic cyst in the peripancreatic region and a history of intermit- tent epigastric pain. Case Report A 53-year-old male patient was referred to our hos- pital with a one-year history of vague discomfort, inter- mittent pain and heat in the epigastric region. The pa- tient was without previously history of illness. Physical examination demonstrated no palpable mass in the ab- dominal region. Results of laboratory tests, including blood counts and biochemical tests were within the nor- mal limits. Abdominal ultrasonography showed a cystic mass adjacent to the pancreas. Computed tomography revealed a well-defined and circumscribed cystic mass with dense fluid content, which measured 8x6x6 cm (Fig. 1). Radiological findings did not show definitive demar-