RIVM, P.O. Box 1, 3720 BA Bilthoven, the Netherlands Tel +31 30 274 91 11 www.rivm.nl RIVM Report 860706002/2007 Exposure and ecological effects of toxic mixtures at field-relevant concentrations Model validation and integration of the SSEO programme Chapter authors: H. J. P. Eijsackers 1 , A. J. Hendriks 2 , C. Klok 3 , A. A. Koelmans 1,4 , F. Kuenen 2,5 , Ch. Mulder 5 , M. Rutgers 5 , P. J. Van den Brink 1,3 , C. A. M. Van Gestel 6 , K. Veltman 2 , S. Wijnhoven 2,7 1 Wageningen University and Research Centre 2 Radboud University, Nijmegen 3 Alterra, Wageningen 4 Wageningen-IMARES, IJmuiden 5 RIVM, Bilthoven 6 Vrije Universiteit Amsterdam 7 (current address) Netherlands Institute of Ecology, Yerseke L. Posthuma (Editor), RIVM M. G. Vijver (Editor), RIVM / University of Leiden Contact: L. Posthuma RIVM - Laboratory for Ecological Risk Assessment L.Posthuma@rivm.nl This study has been funded by a research grant from the Netherlands Organisation for Scientific Research (NWO); it is part of the Stimulation Programme System-Oriented Ecotoxicological Research, an initiative of the Ministries of LNV, V&W, OC&W and VROM.