Imaging of venous nickings 1 1 Venous nicking without arteriovenous contact: A possible role for the 2 arteriolar microenvironment in arteriovenous nickings 3 4 5 Michel Paques, Aurélie Brolly, Jonathan Benesty, Nicolas Lermé, Edouard Koch, 6 Florence Rossant, Isabelle Bloch, Jean-François Girmens 7 8 From the Quinze-Vingts hospital, DHU SightMaintain, INSERM-DHOS CIC 1423, Paris, 9 F-75012 and Université Pierre et Marie Curie-Paris 6, France, the Institut Supérieur 10 d’Electronique de Paris, 75006 Paris, France, and the Institut Mines Telecom, Tel ecom 11 ParisTech, CNRS LTCI, 75013 Paris, France 12 13 Presented in part at the XXIX th Jules Gonin meeting, Zurich (Swiss), September 2014. 14 Supported by the Institut National de la Santé et de la Recherche Médicale (Contrat 15 d’Interface 2011), the Agence Nationale de la Recherche (ANR-09-TECS-009 and ANR-12- 16 TECS-0015-03) and the Association Contre l’OVR (www.asso-ovr.fr). The funding 17 organizations had no role in the design or conduct of this research. 18 Michel Paques is a consultant for the manufacturer of the adaptive optics camera used in 19 this study. 20 Registered in clinicaltrials.gov (NCT01546181) 21 Address for correspondance: Michel Paques, MD, PhD, Clinical Investigation Center 22 1423, Quinze-Vingts hospital, 28 rue de Charenton 75012 Paris, France ; Tel: (33) 1 40 02 23 14 15 Fax : (33) 1 40 02 14 99 mp@cicoph.org 24 25 Word count 1169 26 27