Research Article Impact Assessment of Mercury Accumulation and Biochemical and Molecular Response of Mentha arvensis: A Potential Hyperaccumulator Plant R. Manikandan, 1 S. V. Sahi, 2 and P. Venkatachalam 1 1 Plant Genetic Engineering and Molecular Biotechnology Lab, Department of Biotechnology, Periyar University, Salem, Tamil Nadu 636 011, India 2 Department of Biology, Western Kentucky University, 1906 College Boulevard, No. 11080, Bowling Green, KY 42101-1080, USA Correspondence should be addressed to P. Venkatachalam; pvenkatlab@yahoo.in Received 16 July 2014; Accepted 15 September 2014 Academic Editor: Wendong Tao Copyright © 2015 R. Manikandan et al. his is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. he present study was focused on examining the efect of Hg oxidative stress induced physiochemical and genetic changes in M. arvensis seedlings. he growth rate of Hg treated seedlings was decreased to 56.1% and 41.5% in roots and shoots, respectively, compared to the control. Accumulation of Hg level in both roots and shoots was increased with increasing the concentration of Hg. Superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX) activities were found to be increased with increasing the Hg concentration up to 20 mg/L; however, it was decreased at 25 mg/L Hg concentration. he POX enzyme activity was positively correlated with Hg dose. he changes occurring in the random ampliication of ploymorphic DNA (RAPD) proiles generated from Hg treated seedlings included variations in band intensity, disappearance of bands, and appearance of new bands compared with the control seedlings. It was concluded that DNA polymorphisms observed with RAPD proile could be used as molecular marker for the evaluation of heavy metal induced genotoxic efects in plant species. he present results strongly suggested that Mentha arvensis could be used as a potential phytoremediator plant in mercury polluted environment. 1. Introduction Mercury (Hg) heavy metal pollution is considered as a seri- ous environmental problem throughout the world. Hg is a persistent neurotoxin and it is the only metal in the list of bioaccumulative chemicals of concern. Because of its chemical properties, it exists as an elemental metal in the form of mercuric ions and organomercury. Millions of tons of mercury has been released into the environment as a result of gold mining areas, industrial pollution, metal wastes, burning of fossil fuels, and electronics [1]. In the environment, Hg is converted by sulfate reducing bacteria to the extremely toxic compound methyl mercury which is bioaccumulated in the food chain [2, 3]. As heavy metals such as mercury do not decompose in the environment, efective strategies are needed to remove these compounds from the polluted sites. Environmental restoration of contaminated soils with tradi- tional physical and chemical methods is quite expensive and environmentally invasive and demands extreme investments of economic and technological resources [4]. Heavy metals generally cause damage to plants, either directly or indirectly by triggering an increased level of pro- duction of reactive oxygen species (ROS). hese ROS include superoxide radical (O 2 ∙− ), hydroxyl radical (OH ∙− ), and hydrogen peroxide (H 2 O 2 ) that are produced as byproducts during membrane linked electron transport activities as well as by a number of metabolic pathways. ROS damage the cell membranes, nucleic acids, and chloroplast pigments [5]. Plants have antioxidant systems to protect them against oxidative damage. hese detoxiication processes are complex and highly compartmentalized in plant cells. he level of ROS in the plant is controlled by an antioxidative system that consists of antioxidative enzymes like SOD, CAT, APX, POX, and nonenzymatic low molecular mass antioxidants [6]. SOD is a major scavenger of superoxide anion free radical, which is converted into hydrogen peroxide (H 2 O 2 ) and oxygen Hindawi Publishing Corporation e Scientific World Journal Volume 2015, Article ID 715217, 10 pages http://dx.doi.org/10.1155/2015/715217