Animal Feed Science and Technology 133 (2007) 2–30 Studies on feeds from genetically modified plants (GMP) – Contributions to nutritional and safety assessment G. Flachowsky a,∗ , K. Aulrich b , H. B ¨ ohme a , I. Halle a a Institute of Animal Nutrition, Federal Agricultural Research Centre (FAL), Bundesallee 50, D-38116 Braunschweig, Germany b Institute of Organic Farming, Federal Agricultural Research Centre (FAL), Trenthorst 32, D-23847 Westerau, Germany Abstract Since 1997, 18 studies with feeds from genetically modified plants (GMP) in the nutrition of dairy cows, growing bulls, growing and finishing pigs, laying hens, chicken for finishing as well as growing and laying quails were conducted at the Federal Agricultural Research Centre (FAL) in Braunschweig (Germany). The majority of the experiments (16) were undertaken with GMP of the so-called first generation (plants with input traits and without substantial changes in composition) such as Bt-maize, Pat-maize, Pat-sugar beet, Gt-soybean, Gt-potatoes and Bt-potatoes. Two studies were carried out with GMP of the second generation (plants with output traits or with substantial changes in their chemical composition) such as an altered fatty acids profile in rapeseed or inulin potatoes. In all experiments, feeds from GMP were compared with their isogenic counterparts. The iso- and transgenic feeds were analysed for their composition (proximates, fibre fraction, amino acids, fatty acid pattern, minerals) and undesirable substances (e.g., mycotoxins). Animal studies were carried out for nutritional and safety assessment such as digestibility, feed intake, health and performance of target animal species and quality of food of animal origin. Reproduction was studied in a 10-generation experiment with quails and a 4-generation experiment with laying hens. Duration of experiments and number of animals were limited in some cases due to small amounts of GM-feed available for experimentation. ∗ Corresponding author. Tel.: +49 531 5963101; fax: +49 531 5963299. E-mail address: gerhard.flachowsky@fal.de (G. Flachowsky). 0377-8401/$ – see front matter © 2006 Elsevier B.V. All rights reserved. doi:10.1016/j.anifeedsci.2006.08.002