Hindawi Publishing Corporation
Case Reports in Otolaryngology
Volume 2013, Article ID 925630, 3 pages
http://dx.doi.org/10.1155/2013/925630
Case Report
Mucoepidermoid Carcinoma of the Tongue Base Mimicking
an Ectopic Thyroid
Salvatore Martellucci,
1
Giulio Pagliuca,
1
Marco de Vincentiis,
2
Chiara Rosato,
1
Ettore Scaini,
1
Camilla Gallipoli,
1
and Andrea Gallo
1
1
ENT Section, Department of Surgical Sciences, University of Rome “La Sapienza”, 00192 Rome, Italy
2
ENT Section, Department of Sense Organs, University of Rome “La Sapienza”, 00192 Rome, Italy
Correspondence should be addressed to Salvatore Martellucci; salvomartello@live.it
Received 20 December 2012; Accepted 9 January 2013
Academic Editors: E. Mevio, Y. Orita, and G. Zhou
Copyright © 2013 Salvatore Martellucci et al. his is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
A 69-year-old woman with mucoepidermoid carcinoma (MEC) of the tongue base came under our observation complaining
of repeated episodes of haemoptysis. Mucoepidermoid carcinoma of the tongue base gives rise to a rather vague and aspeciic
symptomatology. Early symptoms include foreign body sensation in the oral cavity, undeined paraesthesia, and sialorrhoea. With
the progression of disease, dysphagia, otalgia, and painful swallowing are usually referred. We report a case of mucoepidermoid
carcinoma of the tongue base mimicking an ectopic thyroid.
1. Introduction
Mucoepidermoid carcinoma (MEC) is a common malignant
salivary gland neoplasm presumed to arise from the reserve
cells of salivary gland ducts. his malignancy originates in
both major and minor salivary glands, although it gen-
erally occurs in the parotid gland (89.6%), followed by
submandibular gland (8.4%). Intraorally, it shows a strong
predilection for the palate [1–3]. MEC was rarely reported
in the tongue base [4, 5]. In this site, a diferential diagnosis
must be made not only with other malignancies but also
with congenital and benign lesions such as ectopic tissues of
thyroidal, epidermal, dermal, venous, and lymphatic origins
[6–9]. We present a case of MEC of the tongue base showing
the gross appearance of an ectopic thyroid and discuss its
clinical presentation.
2. Case Report
A 69-year-old woman came under our observation following
episodes of emophtoe. During the previous 5 months, the
patient experienced sialorrhoea and worsening dysphagia.
Clinical examination revealed the presence of a large, nodu-
lar formation with a smooth surface, richly vascularized,
implanted in the midline of the tongue base (Figure 1). he
macroscopic characteristics of the lesion suggested an ectopic
thyroid diagnosis. CT imaging revealed a solid formation
in the right area of the tongue base measuring 30 mm in
diameter which occupied most of the oropharynx. No locore-
gional adenomegalies were detected. A thyroid scintigraphy
and an ultrasound examination were carried out in order to
determine whether the thyroid was in its normal location
or in an ectopic one. No thyroid tissue was described at the
tongue base, and the thyroid gland was described to be in
its normal position. A selective arteriography of the external
carotid arteries revealed that the mass at the tongue base
was supplied by a rich vascular network deriving from the
terminal branches of the tongue’s artery bilaterally and by
the maxillary artery from the let side. Selective embolization
of the branches feeding the tumor was carried out with the
aim of reducing haemorrhages and minimizing the risks of
bleeding during a bioptic procedure. he histological exami-
nation showed the presence of a low-grade mucoepidermoid
carcinoma originating from the minor salivary glands of the
tongue base. he patient, once informed of the diagnosis and
of the surgical treatment required to remove the neoplasm,
refused to undergo any kind of therapy and was therefore