Research Brief Anxiety Sensitivity in Relation to Sleep Quality Among HIV-Infected Individuals Teresa M. Leyro, PhD Kimberly A. Babson, PhD Marcel O. Bonn-Miller, PhD S leep disturbance is one of the mostprevalent symptomsreportedbyHIV-infectedindividuals (Wheatley & Smith, 1994), with up to 73% reporting significant sleep disturbances (Rubinstein & Selwyn, 1998). Unlike some other symptoms associated with HIV that typically present during the initial phase of illness (e.g., fever, chills, muscle aches), sleep distur- bance has been shown to be present over the course of the disease (Reid & Dwyer, 2005).This is particu- larly concerning as disturbed sleep has been associ- ated with poorer antiretroviral (ART) medication adherence (Babson, Heinz,& Bonn-Miller,2013), viral load (Saberi,Neilands,& Johnson, 2011), greater HIV symptom severity (Babson et al., 2013; Robbins,Phillips,Dudgeon, & Hand, 2004),and higherratesof negative psychological symptoms (Nokes & Kendrew, 2001). While the prevalence and consequences of sleep disturbances amongindividualswith HIV have been established, relatively little work has investi- gated malleable factors that may confer greater risk of sleep disturbances for this population. One rele- vant factor in this area is anxiety sensitivity (AS), a cognitive vulnerability defined as the fear of anxiety, its relevant bodily sensations, and its potential nega- tive social, physical,and mentalconsequences (Taylor et al., 2007). AS has unique relations to sleep disturbances and, among individuals with HIV, spe- cifically,hasbeen linked to greater physiological distress, anxiety, and depressionsymptoms (Gonzalez, Zvolensky, Parent,Grover,& Hickey, 2012;Gonzalez,Zvolensky, Solomon,& Miller, 2010), suicidality (Capron, Gonzalez, Parent, Zvolensky, & Schmidt, 2012),as well as self- reported HIV symptom severity (Leyro, Vujanovic, & Bonn-Miller, in press). Unfortunately, there has been little work in terms of understanding whether greater AS might relate to decrements in sleep quality among individuals with HIV. Drawing from theliteraturemorebroadly, Vincentand Walker (2001) found that, in a sample of adults with chronic insomnia, AS was related to sleep-related impairment, with a trend relation be- tween AS and frequency of medication use, after ac- counting for general worry and presence of Axis I psychopathology. Babson,Trainor,Bunaciu,and Feldner (2008) found that AS interacted with sleep anticipatory anxiety to predict sleep onset latency, a ter accounting fornegativeaffect,gender,age, cannabis use, nicotine dependence, and alcohol use. In a similar investigationconductedamong Teresa M.Leyro,PhD,is an Assistant Professor in the Department of Psychology at Rutgers, The State Universi of New Jersey, New Brunswick, New Jersey, USA. Kimberly A. Babson, PhD, is a Postdoctoral Fellow at the Center for Innovation to Implementation, VA Palo Alto Health Care System and the Department of Psychiatry and Behavioral Sciences,StanfordUniversity,Palo Alto, California, USA. MarcelO. Bonn-Miller, PhD, is a Health Science Specialist at the Center for Innovation to Implementation and NationalCenterfor PTSD, VA Palo Alto Health Care System, Palo Alto, California, USA; Health Science Specialist at the Center of Excellence in Substance Abuse Treatment and Education, Philadelphia VAMC, Philadel- phia, Pennsylvania, USA; and Adjunct Assistant Professor of Psychology in the Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadel- phia, Pennsylvania, USA. JOURNAL OF THE ASSOCIATION OF NURSES IN AIDS CARE,Vol.-, No. -, -/- 2014, 1-8 http://dx.doi.org/10.1016/j.jana.2014.02.002 Copyright Ó 2014 Association of Nurses in AIDS Care