Chitosan combined with conducting polymers for novel functionality:
antioxidant and antibacterial activity
Rudolf Kiefer
1a*
, Rong-Jer Lee
2b
, Rauno Temmer
1c
, Tarmo Tamm
1d
and Alvo Aabloo
1e
1
University of Tartu, Institute of Technology, Tartu, Estonia
2
Industrial Technology Research Institute, Material and Chemistry Lab, Hsinchu, Taiwan
a
rudolf.kiefer@ut.ee,
b
randle@itri.org.tw,
c
rauno.temmer@ut.ee,
d
tarmo.tamm@ut.ee,
e
alvo.aabloo@ut.ee
Keywords: Chitosan, PPy, PEDOT, composites, antioxidants, antibacterial
Abstract
Chitosan as a natural biopolymer has applicable functionality for wound healing due to the
biocompatible and antibacterial properties. Here we investigate what combined biomimetic
functionality can be obtained by forming composites of chitosan and conducting polymers such as
polypyrrole (PPy) or poly(3,4-ethylenedioythiophene) (PEDOT). Chemical polymerization shows
direct interaction between the chitosan matrix and PPy; such materials can be dissolved as stable
suspensions, coated (printed or spin coated) on fabrics or fibers with antioxidant properties of
renewable activity. PEDOT and chitosan composites have shown antibacterial properties against
staphylococcus aureus. The novel biocompatible chitosan conducting polymer composites will give
new direction for obtaining smart materials with diverse functionality, applicable as sensors, food
packaging or ion-selective membranes.
1. Introduction
The difficulty in the processability of chemically or electrochemically obtained conducting
polymers (CP) lies in their insolubility in aqueous solutions. Chitosan obtained from chitin over N-
deacetylation is a natural biopolymer, non-toxic and soluble in light acid, known to show
antimicrobial activity [1]. To increase the solubility of chitosan in aqueous media, certain
depolymerization techniques are applied to obtain chain-scission with oxidants such as ammonium
persulfate (APS) [2], potassium persulfate (PPS) and strong acids. The most common
depolymerization agent of chitosan is perhaps sodium nitrite (NaNO
2
) [3]. Combination of
polypyrrole (PPy) with chitosan forms composites soluble in light acids [4]; and the applied oxidant
(APS: CPC (Chitosan-PPy composites), NaNO
2
: CPPC, (Chitosan-PPy-Porphyrine composites))
determines which modification of composites are formed. Chemically polymerized PPy in form of
powder has been found to be an effective radical scavenger material [5], as shown by the reaction
with di(phenyl)-(2,4,6-trinitrophenyl)-iminoazanium (DPPH) radicals. A new synthetic route on
chitosan-PEDOT composites (CPTC) has been developed to obtain suspensable composites. The
goal of this work is to analyze the conducting polymer chitosan composites in their properties in
antioxidant and antibacterial activity in sensor applications [6, 7].
2. Experimetal
2.1 Chemicals
Chitosan (middle molecular weight, 103,000 g mol
-1
, deacetylation degree 85%), acetic acid (AA,
97%), sodium nitrite (NaNO
2
,97%), ammonium peroxydisulfate ((NH
4
)
2
S
2
O
8
, 98%), ammonium
persulfate (APS, 98%), pyrrole (Py, 98%), 3,4 ethylene dioxythiophene (EDOT, 97%), sodium
Key Engineering Materials Vol. 605 (2014) pp 428-431
Online available since 2014/Apr/03 at www.scientific.net
© (2014) Trans Tech Publications, Switzerland
doi:10.4028/www.scientific.net/KEM.605.428
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