Hindawi Publishing Corporation
Case Reports in Otolaryngology
Volume 2013, Article ID 763201, 4 pages
http://dx.doi.org/10.1155/2013/763201
Case Report
Recurrent Vocal Fold Paralysis and Parsonage-Turner Syndrome
Marcus Vinicius Pinto,
1
Lucia Joffily,
2
and Maurice Borges Vincent
1
1
Department of Neurology, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro,
21941-590 Rio de Janeiro, Brazil
2
Department of Otorhinolaryngology, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro,
21941-590 Rio de Janeiro, Brazil
Correspondence should be addressed to Marcus Vinicius Pinto; mvrpinto@gmail.com
Received 9 August 2013; Accepted 25 September 2013
Academic Editors: Y. Baba and L.-F. Wang
Copyright © 2013 Marcus Vinicius Pinto et al. his is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
Background. Parsonage-Turner syndrome, or neuralgic amyotrophy (NA), is an acute brachial plexus neuritis that typically presents
with unilateral shoulder pain and amyotrophy but also can afect other peripheral nerves, including the recurrent laryngeal nerve.
Idiopathic vocal fold paralysis (VFP) represents approximately 12% of the VFP cases and recurrence is extremely rare. Methods and
Results. We report a man with isolated recurrent unilateral right VFP and a diagnosis of NA years before. Conclusions. We emphasize
that shoulder pain and amyotrophy should be inquired in any patient sufering from inexplicable dysphonia, and Parsonage-Turner
syndrome should be considered in the diferential diagnosis of idiopathic VFP.
1. Introduction
Neuralgic amyotrophy (NA), or Parsonage-Turner syndrome,
is an acute brachial plexus neuritis that typically presents with
unilateral severe shoulder pain followed by patchy paresis and
atrophy [1–3]. Although the pathophysiology of NA remains
obscure, a predisposition for an acute immune attack towards
the peripheral nerves following immunization, infections,
exercise, labor, trauma, or surgery may occur [3, 4]. he
incidence of 2-3 cases per 100,000 [5, 6] a year may not
relect the real igures as NA is for a certainty underdiagnosed.
Idiopathic neuralgic amyotrophy (INA) is ten times more
common than hereditary neuralgic amyotrophy (HNA) [4].
he prognosis is generally good, as 90% of the patients are
almost fully recovered ater 3 years [2].
he NA phenotype may vary to a large extent. Other
segments of the peripheral nervous system (PNS) may be
afected, such as the lumbosacral plexus, phrenic nerve,
and the recurrent laryngeal nerve. he upper trunk of the
brachial plexus is the most afected section, but involvement
of single nerves, as the suprascapular, axillary, and anterior
interosseus nerves, is common. he involvement of the
recurrent laryngeal nerve is rare, particularly in INA [4, 7, 8].
here are only two reports of NA attacks presenting as vocal
fold paralysis without pain or weakness [9, 10].
Unilateral vocal fold paralysis (VFP) is a disorder caused
by dysfunction of the brainstem nuclei, the vague nerve, or
the recurrent laryngeal nerve supplying the involved side of
larynx. Nonlaryngeal malignancy and iatrogenic nerve injury
are the major causes of unilateral VFP, while idiopathic cases
correspond to approximately 12% of the patients [11]. Recent
reports have shown a decrease in idiopathic cases, probably
relecting better diagnostic capabilities [12]. he symptoms
of unilateral VFP are related to immobility of the vocal fold
causing glottic insuiciency. he primary symptom of unilat-
eral VFP is dysphonia, expressed as hoarseness. With time,
it can progress to aspiration of liquids and, in some cases,
exertional dyspnoea [13]. Many cases of idiopathic unilateral
VFP recover spontaneously leading to improvement in voice
quality [11–13]. VFP recurrence is extremely unusual. here
has been only one case of HNA with recurrent isolated VFP
described in a child so far [9].
We report a patient with classical INA years before the
development of recurrent unilateral VFP. To the best of our
knowledge, this is the irst reported case of NA with isolated
recurrent unilateral VFP.