Pharmacognostical and phytochemical evaluation of Angelica archangelica Linn.
Dinesh Kumar, Zulfiqar Ali Bhat*, Vijender Kumar, I. A. Chashoo, N. A. Khan, M. Y. Shah
Department of Pharmaceutical Sciences, University of Kashmir-190006
Key words:
Angelica Archangelica Linn., Physicochemical
parameters, Phytochemical analysis, successive
solvent extraction.
How to Cite this Paper:
Dinesh Kumar, Zulfiqar Ali Bhat, Vijender
Kumar, I. A. Chashoo, N. A. Khan, M. Y. Shah
“Pharmacognostical and phytochemical evaluation of
Angelica Archangelica Linn.”, Int. J. Drug Dev. &
Res., July-Sept 2011, 3(3): 173-188
Copyright © 2010 IJDDR, Zulfiqar Ali Bhat et
al. This is an open access paper distributed under the
copyright agreement with Serials Publication, which
permits unrestricted use, distribution, and
reproduction in any medium, provided the original
work is properly cited.
Introduction
Peoples of all ages in both developing and
undeveloped countries use plants in an attempt to
cure various diseases and to get relief from physical
sufferings. For centuries, plant and plant products
have been used for treating various illnesses. Today,
several medicinal plants and their products are still
International Journal of Drug Development & Research
| July-September 2011 | Vol. 3 | Issue 3 | ISSN 0975-9344 |
Available online http://www.ijddr.in
Covered in Official Product of Elsevier, The Netherlands
©2010 IJDDR
Abstract
Ethnopharmacological relevance: Angelica archangelica
Linn. is a herb distributed in tropical and subtropical regions
of the world. Angelica is largely used in grocery trade as well
as for medicine. The herb is traditionally used for the
treatment of leukoderma, nervous headaches, fever, skin
rashes, wounds, rheumatism, toothaches, gastric ulcers,
anorexia, migraine, bronchitis, chronic fatigue, menstrual and
obstetric complaints and for dental preparation.
Aim of the study: Evaluation of preliminary
Pharmacognostical and phytochemical parameters of Angelica
archangelica Linn.
Material and methods: The whole plant material was
subjected to successive soxhlet extraction with petroleum
ether (40-60
0
C), chloroform, ethyl acetate, methanol and
finally decocted with water to get respective extracts.
Fluorescence characters of powdered material were analysed
under ultraviolet light and ordinary light. Different
physicochemical parameters such as ash value, extractive
value, foaming index, pH values, loss on drying and
determination foreign matter were carried out as per WHO
guidelines. The total fat, flavonoid and saponin contents were
also determined.
Results and discussions: Macroscopical studies revealed
the authentication of plant drug. Physicochemical parameters
helped to standardize the plant material while Preliminary
qualitative chemical test of different extracts showed the
presence of Glycosides, Carbohydrates,
Phytosterols/triterpenoids, Saponins, Fixed oils & Fats and
phenols/tannins. Quantification of total flavonoids, saponins
and fat contents was also carried out.
Conclusion: Results shall pave a way in the standardization
of the drug
*Corresponding author, Mailing address:
Dr. Zulfiqar Ali Bhat
Sr. Asst. Prof. of Pharmacognosy & Phytochemistry, Dept. of
Pharmaceutical Sciences
University of Kashmir, Srinagar (J & K)-190006
Mob.-09419077701; +919882120308
Email: zabhat2000@gmail.com;
sharmadinesh82@gmail.com
Article History:------------------------
Date of Submission: 29-04-2011
Date of Acceptance: 04-05-2011
Conflict of Interest: NIL
Source of Support: UGC- New Delhi
FULL Length Research Paper
Covered in Index Copernicus with IC Value 4.68 for 2010
Int. J. Drug Dev. & Res., July-Sept 2011, 3 (3): 173-188
Covered in Scopus & Embase, Elsevier
173