COMMENTS
©
2006 THE AUTHORS
JOURNAL COMPILATION
©
2006 BJU INTERNATIONAL 1143
CURRENT OPINION AMONGST RADIOLOGISTS AND UROLOGISTS
IN THE UK ON PERCUTANEOUS NEPHROSTOMY AND URETERIC
STENT INSERTION FOR ACUTE RENAL UNOBSTRUCTION: RESULTS
OF A POSTAL SURVEY Mark F. Lynch, Ken M. Anson and
Uday Patel* – Departments of Urology and *Radiology, St George’s Hospital and Medical
School, London, UK
Accepted for publication 14 June 2006
KEYWORDS
percutaneous nephrostomy, ureteric stenting,
guidelines, renal unobstruction
INTRODUCTION
Percutaneous nephrostomy (PCN) and
ureteric stenting have been in clinical use for
the last three or more decades, but there
are still no approved guidelines for the
recommended use of these procedures within
the UK, or indeed elsewhere. Presently there is
controversy on the most effective method of
urinary diversion when unobstruction is
indicated, whether it be PCN or retrograde
ureteric stenting (RUS). Proponents of PCN
cite the relative ease with which a large-
calibre drainage tube can be placed under
sedation, with near 100% success rates [1].
Those who advocate RUS propose that
internal drainage can be placed with less
risk of significant complications and with
no need for external tubes and collection
devices [2].
Many factors influence the decision to
proceed with unobstruction, and there is
limited agreement amongst clinicians about
the optimum timing and method of
intervention. Such consensus would help
healthcare planning, particularly for
‘out-of-hours’ service provision, a topic
already debated in radiological reports
[3–6].
Thus far there have been only two
comparative randomized studies comparing
the performance of PCN and RUS [1,2], with
relatively few patients in each study (42 and
40, respectively), and the studies might have
been under-powered, but at the least they
highlighted several points. Pearle et al. [2]
reported no difference in superiority or
availability of either method, but showed a
higher cost associated with RUS. However,
Mokhmaliji et al. [1] reported a failure rate
of 20% with RUS for stone-induced
hydronephrosis, compared with complete
success with PCN. A further study by
Yossepowitch et al. [7] showed that the
success of RUS was 94% and 73% for intrinsic
and extrinsic ureteric compression,
respectively.
As well as the differences in the technical
success between these procedures they
also diverge in their risk profile. Complication
rates after RUS are not as well reported as
for PCN, but it is generally agreed that
severe bleeding and renal loss have not
been reported. However, there is an
undoubted major complication rate
associated with PCN insertion, with
guidelines recommending that these are
< 4% [8], with a recent series showing that
this value is achievable [9].
In light of the issues on the indications and
means of urgent renal unobstruction, we
composed a postal survey to establish the
level of unanimity or otherwise among
radiologists and urologists in the UK. Various
typical clinical scenarios were constructed,
and accompanying questions were composed
to address the indications for urinary
diversion and the preferred method to
accomplish this. We also evaluated the local
provision of current out-of-hours PCN and
stenting services.
A questionnaire was sent to 153 radiologists
and 132 endourologists within the UK.
Despite a disappointing response of 19.3%
(18.3% of radiologists and 20.5% urologists)
there are issues that arose from the results,
that prompt discussion. There was a broad
similarity in the proportions of radiologists
and urologists choosing de-obstruction in
each clinical scenario, but there was, in some
cases, a complete dichotomy of decision-
making within a group. There were areas of
strong consensus, as in clinical scenarios of
‘clinical sepsis’ or ‘elevated creatinine and
potassium’, where there was 90–100%
agreement amongst all clinicians on the need
for unobstruction. However, when
considering, e.g. ‘ureteric obstruction with
hydronephrosis with advanced malignancy
for palliation’ only half of all respondents
thought that unobstruction was indicated,
highlighting the difficulties faced in this
contentious scenario.
The strongest divergence was that urologists
favoured PCN more often than radiologists
(mean, median and range of percentage
preference for PCN were 48% vs 69%, 49%
vs, 74%, and 6–100% vs 18–100% for
radiologists vs urologists, respectively;
P < 0.001, unpaired t -test). Stents were
preferred by urologist only in patients with
uncomplicated benign disease and in those
with coagulopathy.
Reasons for these differences are speculative,
as current evidence, although not strong,
suggests that the two methods are equally
successful despite each having their strengths
and weaknesses. The analysis of current
service provision in the survey showed only
44% of respondents have an urgent PCN
service every day and night, which seemed a
large proportion compared to the previously
reported values of 11% of hospitals having
a separate interventional radiology on-call
rota [3].
From our discussions with many clinicians,
there seems to be extrinsic logistical and
intrinsic patient factors that influence the
decision of when and how to de-obstruct. The
extrinsic factors are those of availability and
priority of theatre and anaesthetic cover out-
of-hours, and whether the urologist on call is
an experienced endourologist with a high
success rate with difficult stent procedures, or
a less experienced urologist. Some of the
intrinsic or patient factors include the clinical
situation, evidence of pelvic malignancy or
radiotherapy, or chronic upper ureteric
obstruction due to calculi that are difficult to
stent. Decision making in the UK is not
financially driven, as these procedures do not
carry with them any financial reward, unlike
in some other healthcare services. The
anecdotal view of the urologist is that PCN
drainage of an obstructed system is the
technique of choice and more readily
obtained than RUS.
The most significant finding of the present
survey is the absence of a consensus view
about the best method for urgent renal