PP-047 CHADS2 and CHA2DS2-VASc Scoring Systems are not Useful for Predicting Postoperative Atrial Fibrillation after Coronary Artery Bypass Graft Surgery Hasan Güngör 1 , Cemil Zencir 1 , Çagdas ¸ Akgüllü 1 , Ufuk Eryılmaz 1 , Tunay Kurtoglu 2 , Mithat Selvi 1 , Sevil Önay 1 , Mustafa Çetin 3 , Ceyhun Ceyhan 1 , Alper Onbas ¸ılı 1 , Tarkan Tekten 1 1 Adnan Menderes University, Department of Cardiology, Aydin, 2 Adnan Menderes University, Department of Cardiovascular Surgery, Aydin, 3 Adıyaman University, Department of Cardiology, Adiyaman Aim: In recent literature only two data exist whether the CHADS2 and CHA2DS2- VASc scores can be used for the risk assessment of new-onset atrial fibrillation (AF) or AF after coronary artery bypass graft (CABG) surgery. Methods: We retrospectively analyzed 133 consecutive patients (42 patients with AF after CABG surgery and 91 patients without AF) who were undergoing CABG between January 2011 and January 2013 at our department. Complete medical records were retrospectively collected to investigate, congestive heart failure, hypertension, age 75 years, diabetes, previous stroke (CHADS2) and CHA2DS2-vascular disease, age 65-74 years, sex category (CHA2DS2-VASc) scores. The primary end point of this study was the development of AF after CABG surgery in hospital. Results: Only age (67.6+9.7 vs 62.4+10.6 years, p¼0.008) was significantly higher in AF group. Mean CHADS2 and CHA2DS2-VASc scores were 1.53+0.97 and 3.23+1.25 respectively. CHADS2 (1.62+0.91 vs 1.48+1.00, p¼0.34) and CHA2DS2- VASc (3.43+1.17 vs 3.13+1.28, p¼0.22) scores were higher in AF group but it was not statistically significant. When patients divided into two groups according to CHADS2 and CHA2DS2-VASc scores at the cuttof point of 2, no significant difference was detected in AF rate (31.9% vs 30.0%, p¼0.55 and 34.4% vs 24.3%, p¼0.18 respectively). In univariate and multivariate analysis only age was indepen- dent predictor of AF after CABG surgery (Table 1). Conclusıon: CHADS2 and CHA2DS2-VASc scores were not independent predictors of AF after CABG surgery. Further prospective, randomized, controlled trials are necessary to make healthier interpretations on this issue. Congestive Heart Failure PP-048 The Association between Neutrophil/Lymphocyte Ratio and Functional Capacity in Patients with Idiopathic Dilated Cardiomyopathy Abdulkadir Yıldız 1 , Abdullah Tuncez 2 , Enis Grbovic 3 , Nihat Polat 1 , Murat Yuksel 1 , Mesut Aydin 1 , Mustafa Oylumlu 1 , Halit Acet 1 , Mehmet Zihni Bilik 1 , Mehmet Ata Akil 1 , Hasan Kaya 1 , Faruk Ertas 1 , Muhammed Cebeci 3 1 Dicle Universty School of Medicine, Department of Cardiology, Diyarbakir, 2 Konya Numune Hospital, Department of Cardiology, Konya, 3 Turkey Yuksek Ihtisas Training Hospital, Department of Cardiology, Ankara Aim: The neutrophil/lymphocyte ratio (NLR) is an inexpensive, readily available and reliable inflammatory marker which has a predictor value in different cardiovascular disorders. Functional capacity is one of the most important prognostic factor in patients with heart failure. In this study, we aimed to investigate the relationship between NLR and functional capacity (FC) in patients with idiopathic dilated cardiomyopathy (IDC). Methods: Treadmill test according to modified-Bruce protocol was performed in 37 patients with IDC (mean age 46.5 11 years,19% female) to assess their functional capacity. Baseline clinical and echocardiographic variables were obtained. Hemato- logic parameters were measured using an automatic blood counter. Results: The patients were divided into low (<5 METs, n¼18) and high (>5 METs, n¼19) FC groups according to their functional status. There was no significant difference between 2 groups regarding age, sex, echocardiographic parameters, hemoglobin, red cell distribution width (RDW), white blood cell and platelet counts. However, the NLR was significantly higher in low FC group compared to high FC group (3.6 2.4 vs 2.2 0.7, p¼0.007; respectively). There were significant correlations between the NLR and METs, RDW, left ventricular diastolic diameter (r:-0.405, p¼0.013, r:0.613, p<0.001 and r:0.600, p¼0.001; respectively). Diastolic dysfunction was present in all of the patients with low functional capacity. Conclusıon: We detected a significant association between the NLR and low func- tional capacity both of which has predictive and prognostic value in patients with heart failure. Functional capacity may be determined by diastolic function rather than left ventricular ejection fraction. PP-049 The Effects of Vitamin D Supplementation on Exercise Capacity and Echocardiographic Parameters in Patients with Systolic Heart Failure Hakan Muhammed Tas ¸ 1 , Ziya Simsek 1 , Zakir Lazoglu 1 , Murat Akbas 2 , Adem Gungor 2 , Ednan Bayram 1 , Habip Bilen 2 1 Department of Cardiology, Faculty of Medicine, Ataturk University, Erzurum, 2 Department of Endocrinology, Faculty of Medicine, Ataturk University, Erzurum Background and Aim: Low 25-hydroxyvitamin D levels are highly prevalent in heart failure patients. Insufficient Vitamin D levels can cause chronic inflammation and skeletal myopathy that can lead to poor exercise tolerance. We aimed to evaluate vitamin D supplementation in patients with systolic heart failure and its effect on exercise tolerance and echocardiographic parameters. Methods: 54 NHYA Class II or III systolic heart failure patients with 25-hydrox- yvitamin D levels <20ng/ml received 150000 IU of cholecalciferol D3 at baseline and 10 weeks for a total dose of 300000 IU. Patients’ routine medical therapy did not change during the follow-up period. 6-minute walk test (6MWT), echocardiographic measurements and biochemical measurements were made at baseline and 20 weeks. Results: 25 –hydroxyvitamin D levels were significantly increased after 20 weeks (11.6 ng/ml at baseline; 40.720 ng/ml at 20 weeks, p<0.001). 6-MWT were signifi- cantly improved with vitamin D supplementation (461m at baseline; 559.25m at 20 weeks, p<0.001). Ejection fraction with Modified Simpson method significantly increased (31.7% at baseline; 35.50% at 20 weeks, p<0.001) and left ventricular diastolic diameter (60 mm at baseline; 57.95 mm at 20 weeks, p<0.001), left ventricular systolic diameter (50.4 mm at baseline; 48.1mm at 20 weeks, p<0.001) significantly decreased. Left atrium, right atrium and right ventricle sizes, parathyroid hormone concentration, alanine aminotransferase, alkaline phosphatase, calcium and sodium concentration, did not changed significantly. Conclusıon: Vitamin D supplementation on systolic heart failure patients improved exercise capacity, ejection fraction, end-systolic and end-diastolic diameters of left ventricle. Table 1. Predictors of atrial fibrillation after coronary artery bypass graft surgery in multivariate analysis Variables Multivariate analysis, OR (95% CI) P value CHADS2 1.492 (0.580-3.842) 0.41 CHA2DS2-VASc 0.629 (0.251-1.5809 0.32 Body mass index 1.070 (0.986-1.162) 0.10 Age 1.083 (1.011-1.161) 0.02 Left atrial diameter 2.406 (0.721-8.026) 0.15 Mean platelet volume 0.975 (0.898-1.060) 0.56 Clinical, hematological and echocardiographic characteristics of patients according to functional capacity Variable <5METs n¼18 >5METs n¼19 p value Age, years 46 14 47 11 0.761 Male sex, n (%) 16 (88.9) 14 (73.7) 0.238 Hypertension, n (%) 4 (22.2) 6 (31) 0.714 Diabetes, n (%) 4 (22.2) 3 (15.8) 0.693 Body mass index, kg/m2 24.9 3.2 27.3 5.0 0.214 Hemoglobin, g/L 13.8 1.8 14.4 1.1 0.307 Red cell Distribution width 15.5 1.8 14.6 0.6 0.061 Platelet count, /mm3 256 106 241 55 0.625 White blood cell count, x103/mL 8.3 1.6 7.9 1.8 0.605 Neutrophil to lymphocyte ratio 3.6 2.5 2.2 0.7 0.007 QRS duration, msn 104 24 88 21 0.062 Left ventricular diastolic diameter, mm 68 8 65 5 0.645 Left ventricular ejection fraction, % 26 7 28 7 0.426 Diastolic dysfunction, n (%) 18 (100) 13 (68.4) 0.020 JACC Vol 62/18/Suppl C j October 26–29, 2013 j TSC Abstracts/POSTERS C101 POSTERS