Amelioration of untreated restless legs syndrome by tadalafil in a patient with erectile dysfunction. *Andrea Romigi 1,2 , Giuseppe Vitrani 1 ,Alfredo D’Aniello 1 and Giancarlo Di Gennaro 1 1 IRCCS Neuromed Istituto Neurologico Mediterraneo Via Atinense 18 Pozzilli (Is) Sleep Medicine Center 2 Università di Roma Tor Vergata – Neurophysiopathology Department Sleep & Epilepsy Centre Running title: Restless legs syndrome and tadalafil Disclosure statement: This was not an industry supported study. The authors have indicated no financial conflicts of interest. . *Corresponding author: Andrea Romigi, MD, Ph.D. Sleep Medicine Centre IRCCS Neuromed Via Atinense 18 Pozzilli (IS) Phone: +39 0865 929154 Fax: +39 06 97655221 Email: andrea.romigi@gmail.com Keywords: Restless legs syndrome, tadalafil, dopamine, Phosphodiesterase type 5 inhibitor THIS IS A PRE‐PRINT VERSION AND IT IS NOT THE FINAL PUBLISHED VERSION. THE ORIGINAL ARTICLE IS AVAILABLE AT: HTTP://JOURNALS.LWW.COM/CLINICALNEUROPHARM/PAGES/CURRENTTOC.ASPX