Factor analysis - doubling the peak capacity of the column with the help of multi-channel detector and math Yuri A. Kalambet, Sergey Maltsev, Ampersand Ltd., Moscow, Russia; Yuri P. Kozmin, Shemyakin Institute of Bioorganic Chemistry, Moscow, Russia Mailto: kalambet@ampersand.ru Abstract Factor analysis is widely used [1] for separation of incompletely separated chromatographic peaks. We combined this technique with an analysis of the angle derivative of the multi-channel chromatogram to get a better choice of basic spectra. Improvement in the algorithm is demonstrated through examples. The technique used facilitates doubling the peak capacity of the column, as baseline separation requirement is replaced with requirement to separate peaks so, that for every component there is a time point, where it elutes pure.