Research Article Preconception Counseling and Care in the Setting of HIV: Clinical Characteristics and Comorbidities Rupsa C. Boelig, 1 Jenell S. Coleman, 2 Jean Keller, 2 Catherine Sewell, 2,3 and Jean Anderson 2 1 Department of Obstetrics & Gynecology, homas Jeferson University Hospital, Philadelphia, PA 19107, USA 2 Division of Gynecologic Specialties, Department of Obstetrics & Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA 3 Food and Drug Administration, U.S. Department of Health and Human Services, Silver Spring, MD 20993, USA Correspondence should be addressed to Jenell S. Coleman; colemanj@jhmi.edu Received 3 November 2014; Accepted 19 February 2015 Academic Editor: Per Anders Mardh Copyright © 2015 Rupsa C. Boelig et al. his is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To describe the demographic and clinical characteristics of HIV-infected individuals and HIV-afected couples who were referred for preconception counseling (PCC) at a large urban US-based HIV clinic. Methods. Electronic medical records were reviewed for HIV-infected individuals and HIV-afected couples. Medical, reproductive, surgical, psychosocial, and family history data were abstracted. Univariate analyses were done. Results. here were 8 single HIV-infected women and 100 HIV-afected couples who underwent PCC. HIV-infected women were older (mean age 35 years versus 32 years,  = 0.06), were more likely to smoke (23% versus 0%,  < 0.01), and had more medical comorbidities (57% versus 33%,  = 0.04) than HIV-uninfected women. he majority of couples were serodiscordant (77%), and of these couples, 32% had a detectable plasma viral load and 33% report inconsistent condom use. Conclusions. HIV-infected women have a number of medical and psychosocial issues, including those related to HIV that may increase the risk of adverse pregnancy outcomes and HIV perinatal and sexual transmission. PCC is an important intervention to optimize maternal management to improve perinatal outcomes and minimize transmission risks. 1. Introduction Advances in HIV treatment and reductions in perinatal HIV transmission have led to improved quality of life and increased pregnancies among women with HIV [1]. Studies conducted in the era of efective antiretroviral treatment (ART) suggest that HIV-infected women have similar repro- ductive desires and intentions as HIV-uninfected women [2– 4]. Nevertheless, many pregnancies that occur in the setting of HIV are unintended and the most efective forms of reversible contraception are underused [5–8]. Preconception counseling and care (PCC) are associated with improved maternal and fetal outcomes by identifying and modifying risks prior to pregnancy and in preventing unwanted pregnancies [9, 10]. he American College of Obstetricians and Gynecologists and the United States (U.S.) Public Health Services Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission recommend ofering all HIV-infected women of childbearing age comprehensive PCC as a component of routine primary medical care [11, 12]. he goal of PCC in the setting of HIV is to help HIV-infected individuals and HIV-afected couples make informed reproductive decisions, optimize maternal and paternal health prior to pregnancy, improve pregnancy outcomes, and minimize the risk of vertical and/or horizontal transmission. Given the lack of data in the literature regarding the clinical characteristics of individuals presenting for PCC in the setting of HIV, we sought to describe the demographic and clinical characteristics of HIV-infected individuals and HIV-afected couples who were referred for PCC at a large urban US-based HIV clinic. 2. Materials and Methods We conducted a retrospective review of electronic medical records of HIV-infected individuals and HIV-afected cou- ples, where at least one of the partners was HIV infected. A convenience sample of patients referred for PCC at the HIV Hindawi Publishing Corporation Infectious Diseases in Obstetrics and Gynecology Volume 2015, Article ID 240613, 6 pages http://dx.doi.org/10.1155/2015/240613