Research Article The Motor Recovery Related with Brain Lesion in Patients with Intracranial Hemorrhage Kyung Bo Lee, 1 Joon Sung Kim, 1 Bo Young Hong, 1 Young Dong Kim, 2 Byong Yong Hwang, 3 and Seong Hoon Lim 1 1 Department of Rehabilitation Medicine, St. Vincent’s Hospital, College of Medicine, he Catholic University of Korea, 93 Jungbu-daero, Paldal-gu, Suwon 442-723, Republic of Korea 2 Human Movement Research Center, Daejeon 302-852, Republic of Korea 3 Department of Physical herapy, Yongin University, Yongin 449-714, Republic of Korea Correspondence should be addressed to Seong Hoon Lim; seonghoon@catholic.ac.kr Received 25 February 2015; Revised 21 March 2015; Accepted 23 March 2015 Academic Editor: Nicola Tambasco Copyright © 2015 Kyung Bo Lee et al. his is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Although studies have demonstrated that several speciic brain lesions are related to the severity of functional outcomes, the efects of speciic brain lesions are not yet clear. his study investigated the efects of hemorrhagic stroke lesions on motor recovery. Eleven subjects with hemorrhagic stroke were assessed. Using the Fugl-Meyer Assessment and functional ambulation category, clinical motor and sensory impairments were tested four times in total: initially within 2 weeks and 1, 3, and 6 months ater the onset of stroke. Brain lesions and size were evaluated using MRIcron, SPM8, and Talairach Daemon sotware. Trunk control, motor function in the lower limbs, and sensory function improved signiicantly within 3 months, ater which the change was no longer signiicant. Upper limb function and gait were unchanged within 1 month but improved signiicantly 3 months ater onset and continued to improve for 6 months. Involvement of the anterior putamen, internal capsule, thalamus, periventricular white matter, and premotor cortex was related to poor upper limb recovery in patients with hemorrhagic stroke. hese results should be useful for planning rehabilitation strategies and understanding the prognosis of hemorrhagic stroke. 1. Introduction he recovery of motor function, including hand function, sitting, and other motor activities of daily living (ADL), is an important outcome in stroke patients [1]. Several studies have investigated the factors inluencing motor recovery and the relationships between brain lesions and function [2–4]. In these studies, the size of the lesion in the brain was not related to functional outcome [2, 3]. Few studies have reported on the relationships between brain lesions and functional recovery [5–7]. Previously, we revealed patterns of clinical recovery in subacute stroke patients [8]. We want to investigate the efect of stroke lesion on motor recovery. Although studies have demonstrated the efect of brain lesions on functional outcomes, the efects of speciic brain lesions are not yet clear. he primary aim of this study was to investigate the efect of stroke lesion on motor recovery in patients with hemorrhagic stroke. In addition, this study evaluated the recovery pattern of functional ability. 2. Methods 2.1. Study Design and Participants. his was a longitudinal observational clinical trial. Eleven, right handed, subjects with hemorrhagic stroke were recruited from the Department of Rehabilitation Medicine at St. Vincent’s Hospital. All of the subjects had sufered supratentorial intracerebral hemor- rhages (ICH) and met the following criteria: (1) a irst-ever unilateral stroke, (2) ability to follow verbal instructions, (3) inability to walk within 2 weeks ater the ICH, and (4) a Fugl- Meyer Assessment (FMA) score lower than 60 for the upper extremity or lower than 28 for the lower extremity [9]. Exclusion criteria were (1) presence of knee joint efusion determined using US, (2) a history of knee injury or surgery or history of knee injection within 3 months, (3) a history Hindawi Publishing Corporation Behavioural Neurology Volume 2015, Article ID 258161, 6 pages http://dx.doi.org/10.1155/2015/258161