Research J. Pharm. and Tech. 9(5): May 2016 1 ISSN 0974-3618 (Print) www.rjptonline.org 0974-360X (Online) RESEARCH ARTICLE Pattern of Analgesic Use in Post-Operative Pain Management in a Tertiary Level Teaching Hospital in Bangladesh Morshed Nasir 1 , Rawshon Ara Parveen 2 , Nazmun Nahar Alam 3 , 1 Professor, Department of Pharmacology, Holy Family Red Crescent Medical College, Dhaka, Bangladesh. 2 Assistant Professor, Department of Pharmacology, Holy Family Red Crescent Medical College, Dhaka, Bangladesh. 3 Lecturer, Department of Pharmacology, Holy Family Red Crescent Medical College Dhaka, Bangladesh. *Corresponding Author E-mail: morshednasir@hotmail.com ABSTRACT: Recent advance in the knowledge of pathophysiology of pain and improvement of analgesic drugs and techniques, little improvement will show in post- operative pain management in LUCS. Like most other post- surgical populations, the new mother needs effective pain relief so that she can mobilise early but she also has the added responsibility of needing to care for her newborn baby. There is no 'gold standard' for post-caesarean pain management. This prospective observational study was done to observe the prescribing trend of analgesic used in per and post- operative patients of LUCS of gynae and obstratic department of Holy Family Red Crescent Medical College Hospital. A total of normotensive and non- diabetic 111 patients were included over 6 month period of January 2015 to July 2015. Analgesics prescribed for pain management used from during and after day of operation to 4 th post- operative day were recorded. 31.03% patient received pethidine and 21.29% received fentanyl preoperatively, 91.60% patient received pethidine on the day of operation. Diclofenac (78.70%) was most commonly prescribed drug in post- operative days. Seven different strength of pethidine used per-operatively. Ten different combination of analgesics used in patients, among them pethidine and diclofenac combination used in highest cases. KEYWORDS: Analgesics, Post operative, Pain, INTRODUCTION: Most common operation of gynecology and obstetrics ward is lower uterine caesarian section. Since 1985, the international healthcare community has considered the ideal rate for caesarean sections to be between 10-15%. Since then, caesarean sections have become increasingly common in both developed and developing countries. When medically necessary, a caesarean section can effectively prevent maternal and newborn mortality 1 . Received on 14.02.2016 Modified on 20.02.2016 Accepted on 22.02.2016 © RJPT All right reserved Research J. Pharm. and Tech. 9(5): May, 2016; Page 1-3 DOI: Several studies have enumerated the undesirable consequences of inadequately treated postoperative pain. These include both physiological and psychological consequences resulting in increased catabolic response, increased morbidity and prolong hospital stay 2 . Like most other post-surgical populations, the new mother needs effective pain relief so that she can mobilize early. Adequate pain relief, as early mobilization is a key factor to prevent the risk of thrombo-embolic disease, which is increased during pregnancy. But she also has the added responsibility of needing to care for her newborn baby 3 . The pattern of management varies between centers. Caesarean section (CS) commonly induces moderate to severe pain for 48 hours. Analgesics are defined as the drugs that relieve pain without blocking nerve impulse conduction or markedly altering sensory function. Based on the type of relieving action, they are classified into two. Opioids inhibit pain impulses by acting on brain