CONCLUSION: Results of this study demonstrate that prenatal care that includes Neevo Ò /NeevoDHA Ò may decrease rates of anemia in pregnancy. Further studies are warranted. Supported by: Pamlab, L.L.C. P-464 Wednesday, October 27, 2010 END OF A MEANS OR MEANS OF AN END?-TOWARDS A BETTER INDEX FOR EVALUATION OF THE POTENTIAL OF REPRODUC- TIVE HEALTH SCIENTISTS COMPETING FOR POSTS, GRANTS OR FELLOWSHIPS. A. Y. Shahin. Obstetricsand Gynecology, Women’s Health Center, Assiut, Egypt. OBJECTIVE: The current approaches institutes are using for evaluation of scientists applying for posts, grants and fellowships are lacking universality. Scientific disciplines differ in readership volume, hence citations, h-index and final evaluation of individuals applying for posts. The prediction of the potential of these individuals in terms of productivity and impact of their fu- ture scientific output is desired to help comittees to take the proper decision. We try to prove that the h-index is not suitable for the choice of scientists ap- plying for competitive positions in reproductive science. We propoe a new method of evaluation. DESIGN: A mathematical analysis of Journal citation report and data from the web of science (ISI). MATERIALS AND METHODS: We reviewed publications, citations and journal citation reports in different disciplines over the last 10 years. A math- ematical normalization was conducted in order to reach the proper index to evaluate reproductive scientists. We propose a new equation for scientific and institutional evaluation that depends upon number of papers, recent publica- tions, h-index, mean position index, number of citations and article influence score as well as immediacy index. RESULTS: We created a new P-index that has the merits of being simple, utilizing the h-index, avoiding its limitations, representing the potential of candidates and being suitable for both young and esablished scientists in re- productive Medicine. The index can also be modified to suit all disciplines, as we show from our results. CONCLUSION: The use of the new P-index can successfully predict ca- reer development of candidates applying for posts on competitive basis, and it avoids the h-index limitations. ENVIRONMENT AND REPRODUCTION P-465 Wednesday, October 27, 2010 ALL PATIENTS SEEKING INFERTILITY SERVICES SHOULD BE IMMUNIZED AGAINST H1N1: ESTIMATION OF THE IMPACT OF H1N1 IMMUNIZATION ON MATERNAL MORBIDITY AND MORTALITY IN INFERTILITY PATIENTS. C. E. Alford, A. H. DeCherney, A. Y. Armstrong. Program in Reproductive and Adult En- docrinology, Eunice Kennedy Shriver, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD. OBJECTIVE: In preparation for the 2010 and 2011 pandemic of H1N1 in- fluenza, our objective was to estimate the impact of the H1N1 immunization in women presenting with a diagnosis of infertility. DESIGN: Decision tree model with sensitivity analysis. MATERIALS AND METHODS: The number of infertility visits, H1N1 vaccination rate, H1N1 infection rate, obstetric patients hospitalized with H1N1, and maternal death rate from H1N1 were estimated using data from the National Survey of Family Growth (NSFG), the CDC, and from a PubMed search. We used a decision tree model with sensitivity analysis to estimate the number of hospitalizations and deaths in pregnant women that could be prevented by the H1N1 immunization. RESULTS: According to the NSFG 2002 report, 7.3 million reproductive- aged women have sought infertility services. Assuming a pregnancy rate range of 10% to 50% in this population, 730,000-3,650,000 women would become at risk for H1N1 obstetric (OB) complications. Given the H1N1 in- fection rate in reproductive-aged women of 6.97-26.7/100,000, the model es- timated 51-975 pregnant women likely to acquire the disease. The H1N1 hospitalization rate for OB patients was 18%; therefore 9-175 hospitaliza- tions in pregnant women would be expected. The H1N1 death rate in hospi- talized OB patients was 41% and modeling estimated that 4-72 deaths could be prevented by the H1N1 immunization. At the current immunization rate of 23.9%, up to 17.5 maternal deaths may have been prevented by the H1N1 im- munization. With a 100% immunization rate, 72 deaths could be prevented. H1N1 Immunization Rate (%) Potential Maternal Hospitalizations Prevented Potential Maternal Deaths Prevented 25 44 18 50 88 36 75 131 54 100 175 72 CONCLUSION: Universal immunization of patients undergoing infertil- ity treatment was estimated to markedly decrease maternal morbidity and mortality associated with H1N1. All patients undergoing IVF should be encouraged to undergo H1N1 immunization. Supported by: Intramural research PRAE, NICHD, NIH. P-466 Wednesday, October 27, 2010 PERFLUOROOCTANOIC ACID, AN ENVIRONMENTAL TOXIN, CONFERS NO ADVERSE EFFECT ON SEMEN PARAMETERS. S. K. Dahl, J. C. Robins, D. B. Williams, A. Kubatova, D. H. Wu, M. A. Thomas. Department of Obstetrics and Gynecology, The University of Cincinnati Academic Health Center, Cincinnati, OH; Chemistry Depart- ment, University of North Dakota, Grand Forks, ND. OBJECTIVE: Perfluorooctanoic acid (PFOA) is used in the production of numerous industrial and consumer products. It is an environmental toxin pre- viously linked to delayed time to conception in women, prostate cancer and decreased sperm counts in men. The object of this study was to determine if PFOA accumulates in seminal fluid and if it has an effect on sperm parame- ters in men. DESIGN: Prospective study of males presenting for routine semen analy- sis (SA). MATERIALS AND METHODS: All male participants completed a ques- tionnaire regarding exposure to products containing PFOA and other envi- ronmental toxins. Both serum and seminal fluid samples were obtained. SA was performed and analyzed by WHO criteria. Serum and seminal fluid concentrations of PFOA were determined by liquid chromatography/mass spectrometry. Scatter plots and multiple regression analysis were used to de- termine the relationship between serum and seminal PFOA levels and semen parameters. RESULTS: Thirty-seven men participated in the study. PFOAwas detected in the plasma of all study subjects with a range of 2.1-103.7 ppb and mean concentration of 21.3  24.5 ppb. Four subjects (10.8%) had detectable levels of PFOA in the seminal fluid with a range of 1.35-12.05 ppb. PFOA had no effect on sperm count, motility, or morphology. CONCLUSION: PFOA was detectable in the serum of men who presented for routine SA at concentrations higher than previously reported in the gen- eral population. This is an important finding because PFOA does not degrade in the environment and persists in human tissue with a long half life. This study confirmed that PFOA accumulates in seminal fluid. However, despite seemingly high concentrations of PFOA, exposure was not associated with adverse effects on sperm parameters. Longitudinal studies are necessary to determine if long term adverse consequences of PFOA accumulation in sem- inal fluid could possibly include infertility, formation of testicular tumor, or alterations in the production of gonadal steroid hormones. Supported by: Patty Brisben Foundation. P-467 Wednesday, October 27, 2010 URINARY BISPHENOL A (BPA) CONCENTRATIONS AND OVAR- IAN RESPONSE IN WOMEN UNDERGOING OVULATION INDUC- TION/INTRAUTERINE INSEMINATION CYCLES (OI/IUI). I. Souter, I. Dimitriadis, S. Ehrlich, J. C. Petrozza, J. B. Ford, R. Hauser. Obstetrics,Gy- necology and Reproductive Biology, Massachusetts General Hospital-Har- vard Medical School, Boston, MA; Environmental Health, Environmental and Occupational Medicine and Epidemiology Program, Harvard School of Public Health, Boston, MA. OBJECTIVE: To determine the association between urinary BPA concen- trations and ovarian response among women undergoing OI/IUI. FERTILITY & STERILITY Ò S227