NECSI Report 2010-08 The Rationale for System-Level Strategies of Infection Control Luci Leykum South Texas Veteran’s Health Care System University of Texas Health Science Center at San Antonio 7703 Floyd Curl Drive, Department of Medicine San Antonio, Texas, USA Yaneer Bar-Yam New England Complex Systems Institute 238 Main St Suite 319 Cambridge, Massachusetts, USA Manuscript completed May 19, 2009 Posted online August 17, 2010 238 Main Street #319, Cambridge, MA 02142 T 617-547-4100 F 617-661-7711 www.necsi.edu New England Complex Systems Institute