Research Article Clinical Manifestations Associated with Overweight/Obesity in Puerto Ricans with Fibromyalgia Syndrome Ruth M. Fred-Jiménez, 1 Mariangelí Arroyo-Ávila, 1 Ángel M. Mayor, 1,2 Grissel Ríos, 1 and Luis M. Vilá 1 1 Division of Rheumatology, Department of Medicine, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936, USA 2 Retrovirus Research Center, Department of Internal Medicine, Universidad Central del Caribe School of Medicine, Bayam´ on, PR 00960, USA Correspondence should be addressed to Luis M. Vil´ a; luis.vila2@upr.edu Received 9 July 2015; Revised 18 December 2015; Accepted 21 December 2015 Academic Editor: Francesco Saverio Papadia Copyright © 2016 Ruth M. Fred-Jim´ enez et al. his is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To determine the clinical manifestations associated with overweight/obesity in Hispanics from Puerto Rico with ibromyalgia syndrome (FMS). Methods. A cross-sectional study was performed in 144 patients with FMS (per American College of Rheumatology (ACR) classiication criteria). Sociodemographic features, FMS-related symptoms, tender points (per ACR criteria), comorbidities, and FMS treatment were examined. BMI was calculated and patients were grouped into two categories: BMI ≤ 24.9 kg/m 2 (nonoverweight/obese) and BMI ≥ 25 kg/m 2 (overweight/obese). Bivariate and multivariate analyses were used to evaluate diferences between the study groups. Results. he mean (standard deviation (SD)) age of patients was 50.2 (9.9) years; 95.1% were females and 75.7% were overweight/obese. In the bivariate analysis, overweight/obese patients were more likely to have self-reported memory impairment, anxiety, shortness of breath, and urinary frequency than nonoverweight/obese patients. In addition, the tender point count was higher in the overweight/obese group. In the logistic regression analyses, self-reported memory impairment and urinary frequency diferences remained signiicant ater adjusting for confounding variables. Conclusion. In this population of Puerto Ricans with FMS, overweight/obese patients experienced more FMS-related manifestations than nonoverweight/obese individuals. However, prospective studies are needed to conirm these associations and to elucidate if weight reduction interventions could favorably impact the severity of FMS. 1. Introduction Fibromyalgia syndrome (FMS) occurs predominantly in women and is characterized by difuse musculoskeletal pain, tiredness, sleep disorder, headaches, and cognitive impairment, among several other manifestations [1, 2]. he exact pathogenesis of FMS remains to be elucidated as well as the contributing factors associated with the severity of symptoms [3–6]. Obesity and overweight status are common comorbidities in FMS patients [3, 4, 7]. Obesity is associated with increased sensitivity to pain, poor health status, and a low health-related quality of life [8–10]. Because obesity and FMS share some clinical features it is not surprising that some studies have found that FMS patients with obesity have worse symptoms including higher pain perception, lower physical strength, poorer sleep quality, and lower self- reported quality of life [3, 4, 6]. In addition, obesity was found to be an independent risk factor for FMS in a longitudinal cohort of Norwegian women [11]. he full spectrum of FMS manifestations has not been fully studied in overweight/obese FMS patients. hus, we sought to examine the clinical manifestations associated with overweight/obesity in a group of Puerto Ricans with FMS. 2. Methods 2.1. Patient Population. A cross-sectional study was per- formed in adult (≥21 years) Puerto Rican patients with FMS, Hindawi Publishing Corporation Journal of Obesity Volume 2016, Article ID 1379289, 7 pages http://dx.doi.org/10.1155/2016/1379289