Characterization of donor dendritic cells and enhancement of dc efflux with cc- chemokine ligand 21: a novel strategy to prolong islet allograft survival Received on 13 October 2006 and accetped in revised form 15 January 2007. Paolo Fiorina 1,3* , Mollie Jurewicz 1* , Katsunori Tanaka 1 , Negin Behazin 1 , Andrea Augello 1 , Andrea Vergani 1,3* , Uli Von Adrian 4 , Neal R. Smith 2 , Mohamed H. Sayegh 1 , and Reza Abdi 1 1 Transplantation Research Center (TRC), Children’s Hospital and Brigham and Women's Hospital, Harvard Medical School, Boston, USA; 2 Pathology, Massachusetts General Hospital, Harvard Medical School, Boston; 3 Medicine, San Raffaele Scientific Institute, Milan, Italy; 4 CBR Institute for Biomedical Research and Department of Pathology, Harvard Medical School, Boston, USA. *PF and MJ contributed equally to this work. Running title: Chemokine-based therapy to reduce direct allorecognition Address for correspondence: Reza Abdi, MD Transplantation Research Center (TRC) Children’s Hospital and Brigham and Women's Hospital Harvard Medical School 221 Longwood Avenue Boston, MA 02115 E-mail: rabdi@rics.bwh.harvard.edu This article includes an Online Appendix. 1 Diabetes In Press, published online February 7, 2007 Copyright American Diabetes Association, Inc., 2007