Eur Arch Otorhinolaryngol (2009) 266:1681–1686 DOI 10.1007/s00405-009-1085-6 123 REVIEW ARTICLE Outcome of conservation surgery for laryngeal carcinoma: an 8-year trial Bilge Tuna · Hüseyin KatÂlmÂo · Sedat Öztürkcan · Ali Ekber Ãlknur · RÂza Dündar · YÂlmaz Özkul · Sinem Aktao · Filiz Gülistan Received: 9 March 2009 / Accepted: 24 August 2009 / Published online: 16 September 2009  Springer-Verlag 2009 Abstract The purpose of this report is to review the expe- rience of our institution with conservative surgery for laryngeal cancer. In this retrospective study, a review was made of 85 patients treated with conservation surgery between 1998 and 2005. At least 2 years of follow-up period (mean 46.6 months) was achieved for all the patients. We evaluated age, tobacco and alcohol intake, T stage, histopathological diVerentiation and localization of tumor, subglottic extension, anterior commissure invasion, vocal cord mobility, surgical margins, type of surgery applied, and post-operative radiotherapy (pRT) applied. Local control and 2-year survival rates were estimated. We managed with horizontal, vertical, and horizontovertical laryngectomies in 55, 26, and 4 patients, respectively. 28 patients were scheduled to have pRT. The actuarial and overall local control rates were 82.4 and 94.1%, respec- tively. On univariable analysis, signiWcant factors for increased recurrences were positive resection margins, low diVerentiation of tumor, alcohol consumption and incom- pletion of the planned pRT. The 2-year survival rate was 60 and 95.7% for patients with and without local recurrence, respectively. Conservation surgery is a safe procedure for laryngeal cancer in proper endications. Keywords Conservation surgery · Laryngeal cancer · Local recurrence Introduction Laryngeal cancer is one of the most common types of head and neck cancer. While the optimal primary treatment for laryngeal cancer continues to evolve, surgical resection remains a common choice and is often chosen based upon the extent of the disease and the treating clinician’s experi- ence and comfort level in performing organ preservation laryngeal surgery techniques [1]. The aim of the partial sur- gery is total removal of the tumor and maintaining laryn- geal function. Today we have several treatment modalities with diVerent morbidity results [2]. The purpose of this report is to review the experience of our institution with conservative surgery for laryngeal can- cer to assess the eVectiveness of treatment and to identify tumor, patient, and treatment factors that may inXuence local control and could therefore be used to improve our management of laryngeal cancer. Materials and methods From January 1998 to December 2005, 325 patients with SCC of the larynx were treated with primary surgery at the 2nd Department of Otolaryngology of Ãzmir Ataturk Train- ing and Research Hospital. The group was composed of B. Tuna (&) Department of Otorhinolaryngology and Head and Neck Surgery, Nizip State Hospital, Ministry of Health, Gaziantep, Turkey e-mail: bidem66@hotmail.com H. KatÂlmÂo · S. Öztürkcan · A. E. Ãlknur · S. Aktao · F. Gülistan Department of Otorhinolaryngology and Head and Neck Surgery, Ãzmir Atatürk Research and Training Hospital, Ministry of Health, Izmir, Turkey R. Dündar Department of Otorhinolaryngology and Head and Neck Surgery, Ankara Etimesgut Military Hospital, Ankara, Turkey Y. Özkul Department of Otorhinolaryngology and Head and Neck Surgery, Malatya State Hospital, Ministry of Health, Malatya, Turkey