Research Article
Neck Circumference as a Predictive Indicator of CKD for
High Cardiovascular Risk Patients
Ya-Fang Liu,
1,2
Shih-Tai Chang,
3
Wei-Shiang Lin,
4
Jen-Te Hsu,
3
Chang-Min Chung,
3
Jung-Jung Chang,
3
Kuo-Chun Hung,
5
Kang-Hua Chen,
6
Chi-Wen Chang,
6
Fu-Chi Chen,
7
Yun-Wen Shih,
8
and Chi-Ming Chu
1,8
1
Graduate Institute of Life Sciences, National Defense Medical Center, No. 161, Section 6, Minquan East Road, Neihu District,
Taipei City 114, Taiwan
2
Department of Education and Research, Shin Kong Wu Ho-Su Memorial Hospital, No. 95, Wenchang Road, Shilin District,
Taipei City 111, Taiwan
3
Division of Cardiology, Chiayi Chang Gung Memorial Hospital, No. 6, West Section Chiapu Road, Putzu City,
Chiayi Hsien 613, Taiwan
4
Division of Cardiology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, No. 325,
Section 2, Chenggong Road, Neihu District, Taipei City 114, Taiwan
5
Division of Cardiology, Department of Internal Medicine, Chang Gung Memorial Hospital,
Chang Gung University College of Medicine, No. 5, Fuxing Street, Guishan District, Taoyuan City 333, Taiwan
6
School of Nursing, College of Medicine, Chang Gung University, No. 259, Wenhua 1st Road, Guishan District,
Taoyuan City 333, Taiwan
7
Department of Biomedical Engineering, National Defense Medical Center, No. 161, Section 6, Minquan East Road,
Neihu District, Taipei City 114, Taiwan
8
Section of Biostatistics and Informatics, Department of Epidemiology, School of Public Health, National Defense Medical Center,
Room 4317, No. 161, Section 6, Minquan East Road, Neihu District, Taipei City 114, Taiwan
Correspondence should be addressed to Chi-Ming Chu; chuchiming@web.de
Received 15 July 2014; Revised 2 December 2014; Accepted 5 January 2015
Academic Editor: Jamal H. Hashim
Copyright © 2015 Ya-Fang Liu et al. his is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background. Neck circumference (NC) is an anthropometric measure of obesity for upper subcutaneous adipose tissue distribution
which is associated with cardiometabolic risk. his study investigated whether NC is associated with indicators of chronic kidney
disease (CKD) for high cardiometabolic risk patients. Methods. A total of 177 consecutive patients who underwent the outpatient
departments of cardiology were prospectively enrolled in the study. he patients were aged >20 years with normal renal function
or with stages 1–4 CKD. A linear regression was performed using the Enter method to present an unadjusted
2
, standardized
coeicients, and standard error, and the Durbin-Watson test was used to assess residual independence. Results. Most anthropometric
measurements from patients aged ≧65 were lower than those from patients aged <65, except for women’s waist circumference (WC)
and waist hip ratio. Female NC obtained the highest
2
values for 24 hr CCR, uric acid, microalbuminuria, hsCRP, triglycerides, and
HDL compared to BMI, WC, and hip circumference. he signiicances of female NC with 24 hr CCR and uric acid were improved
ater adjusted age and serum creatinine. Conclusions. NC is associated with indicators of CKD for high cardiometabolic risk patients
and can be routinely measured as easy as WC in the future.
1. Introduction
Cardiovascular disease (CVD) and chronic kidney disease
(CKD) are two important global public health concerns
that share common cardiometabolic risk factors that include
hypertension, diabetes mellitus, and hyperlipidemia. he
above three diseases generally coexist, making them the most
common risk factors for CVD [1]. In 2007, the Taiwan Health
Hindawi Publishing Corporation
BioMed Research International
Volume 2015, Article ID 745410, 11 pages
http://dx.doi.org/10.1155/2015/745410