www.elsevier.nl/locate/ica Inorganica Chimica Acta 297 (2000) 389 – 399 New hexanuclear and octanuclear iron(III) oxide clusters: octahedral [Fe 6 O 2 ] 14 + species and core isomerism in [Fe 8 O 4 ] 16 + complexes Euan K. Brechin a , Michael J. Knapp b , John C. Huffman a , David N. Hendrickson b, * 1 , George Christou a, * 2 a Department of Chemistry and Molecular Structure Center, Indiana Uniersity, Bloomington, IN 47405 -7102, USA b Department of Chemistry, Uniersity of California at San Diego, La Jolla, CA 92093 -0358, USA Received 1 July 1999; accepted 20 August 1999 Abstract The synthesis, X-ray crystal structures and magnetic properties of two new classes of hexanuclear and octanuclear iron(III) clusters are reported. The reaction of hmpH (2-(hydroxymethyl)pyridine) with [Fe 3 O(O 2 CR) 6 (H 2 O) 3 ](NO 3 ) (R =Bu t , Ph) gives [Fe 6 O 2 (O 2 CR) 6 (hmp) 6 ](NO 3 ) 2 containing a Fe III 6 octahedron with two opposite faces bridged by 3 -O 2 - ions. Similar reactions employing FeCl 3 /NaO 2 CR (R =Me, Ph) give [Fe 8 O 4 (O 2 CPh) 11 (hmp) 5 ] and [Fe 8 O 4 (O 2 CMe) 12 (hmp) 4 ]. Both contain a similar [Fe 8 ( 3 -O) 4 ] core that can be described as four triangular [Fe 3 O] units joined together by edge or vertex sharing or, alternatively, as two [Fe 3 O] units bridged by a [Fe 2 O 2 ] rhombus; however, the dispositions of the [Fe 3 O] units about the [Fe 2 O 2 ] central unit differ in the two complexes and can be described as syn and anti core isomers. The Fe 6 and Fe 8 complexes have been found to have S =0 ground states when studied by variable-temperature, solid-state magnetic susceptibility measurements, consistent with the expected antiferromagnetic exchange interactions between the Fe(III) ions. © 2000 Elsevier Science S.A. All rights reserved. Keywords: Iron complexes; Polynuclear complexes; Magnetism; Crystal structures 1. Introduction Polynuclear ironoxo complexes have been of inter- est from a number of viewpoints. From a biological point of view, ironoxo clusters of various sizes have represented model systems for the build up of the ironoxo core of the iron storage protein ferritin [1,2], or for biomineralization processes that form a variety of ironoxo minerals such as ferrihydrite, goethite, etc. [3]. Ironoxo clusters have also been of interest from a materials point of view; discrete molecular species offer the potential of acting as precursors to molecule-based magnetic materials and even of functioning as nano- scale magnetic particles themselves [4]. As a result of these and other stimuli, a wide variety of such clusters with aesthetically pleasing structures and interesting magnetic properties have been prepared and studied over the last 15 years or so [5–19]. The continuing development of the above areas re- quires the discovery of new examples on a regular basis, and we have thus been investigating new synthetic procedures capable of allowing access to new structural types. One approach has been to use appropriately chosen chelates to encourage aggregation while ensur- ing discrete products that are soluble and can be purified and crystallized. In this paper we describe the use of the anion of 2-(hydroxymethyl)pyridine (hmp - ) in reaction systems that lead to Fe 6 and Fe 8 products that represent new structural types in ironoxo cluster chemistry, and show that syn, anti core isomerism is possible for the Fe 8 species. 1 * Corresponding author. 2 * Corresponding author. Tel./fax: +1-812-855-2399. 0020-1693/00/$ - see front matter © 2000 Elsevier Science S.A. All rights reserved. PII:S0020-1693(99)00377-1