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Amsterdam: Academic Medical Center, 2005; May Received for publication: 16.6.09; Accepted in revised form: 25.3.10 Nephrol Dial Transplant (2010) 25: 3325–3332 doi: 10.1093/ndt/gfq215 Advance Access publication 15 April 2010 Determinants of eGFR at start of renal replacement therapy in paediatric patients Karlijn J. van Stralen 1 , E. Jane Tizard 2 , Kitty J. Jager 1 , Franz Schaefer 3 , Karel Vondrak 4 , Jaap W. Groothoff 5 , Ludmila Podracká 6 , Christer Holmberg 7 , Augustina Jankauskiené 8 , M. A. Lewis 9 , Rita van Damme-Lombaerts 10 , Conceição Mota 11 , Patrick Niaudet 12 , Gregor Novljan 13 , Amira Peco-Antic 14 , Emilija Sahpazova 15 , Ülle Toots 16 and Enrico Verrina 17 1 ESPN/ERA–EDTA Registry, Department of Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, 2 Department of Paediatric Nephrology, Bristol Royal Hospital for Children, Bristol, UK, 3 University of Heidelberg Children’ s Hospital, Heidelberg, Germany, 4 Department of Paediatrics, University Hospital Prague-Motol, Prague, Czech Republic, 5 Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands, 6 Department of Pediatrics, University Hospital, Kosice, Slovakia, 7 Department of Pediatric Nephrology, Helsinki University Hospital, Helsinki, Finland, 8 Vilnius University Children Hospital, Vilnius, Lithuania, 9 Department of Paediatric Nephrology, Royal Manchester Children’ s Hospital, Manchester, UK, 10 Department of Paediatric Nephrology and Organ Transplantation, University Hospital Leuven, Leuven, Belgium, 11 Department of Pediatric Nephrology, Centro Hospitalar do Porto, Porto, Portugal, 12 Hôpital Necker—Enfants Malades, Paris, France, 13 Department of Pediatric Nephrology, University Medical Center Ljubljana Children’ s Hospital, Ljubljana, Slovenia, 14 University Children’ s Hospital, Belgrade, Serbia, 15 Department of Nephrology, Pediatric Clinic, Skopje, Macedonia, 16 SA Tallinna Lastehaigla, Tallinn, Estonia and 17 Nephrology, Dialysis and Transplantation Unit, G. Gaslini Institute, Genoa, Italy Correspondence and offprint requests to: Karlijn van Stralen; E-mail: K.J.vanStralen@amc.uva.nl Abstract Background. Few studies have investigated the determi- nants of glomerular filtration rate (GFR) in paediatric pa- tients starting on dialysis or with a transplant. Methods. Data were collected as part of the European Society of Paediatric Nephrology/European Renal Association–European Dialysis and Transplant Association registry from 14 European countries and referred to incident Determinants of eGFR at start of RRT in paediatric patients 3325 © The Author 2010. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org by guest on August 28, 2016 http://ndt.oxfordjournals.org/ Downloaded from